Gohlke U - Search Results

1

Internal Dynamics of the 3-Pyrroline-N-Oxide Ring in Spin-Labeled Proteins.

Consentius P, Loll B, Gohlke U, Alings C, Müller C, Müller R, Teutloff C, Heinemann U, Kaupp M, Wahl MC, Risse T. Consentius P, et al. Among authors: gohlke u. J Phys Chem Lett. 2017 Mar 16;8(6):1113-1117. doi: 10.1021/acs.jpclett.6b02971. Epub 2017 Feb 23. J Phys Chem Lett. 2017. PMID: 28221042

2

Combining EPR spectroscopy and X-ray crystallography to elucidate the structure and dynamics of conformationally constrained spin labels in T4 lysozyme single crystals.

Consentius P, Gohlke U, Loll B, Alings C, Heinemann U, Wahl MC, Risse T. Consentius P, et al. Among authors: gohlke u. Phys Chem Chem Phys. 2017 Aug 9;19(31):20723-20734. doi: 10.1039/c7cp03144k. Phys Chem Chem Phys. 2017. PMID: 28740983

3

Tracking Transient Conformational States of T4 Lysozyme at Room Temperature Combining X-ray Crystallography and Site-Directed Spin Labeling.

Consentius P, Gohlke U, Loll B, Alings C, Müller R, Heinemann U, Kaupp M, Wahl M, Risse T. Consentius P, et al. Among authors: gohlke u. J Am Chem Soc. 2016 Oct 5;138(39):12868-12875. doi: 10.1021/jacs.6b05507. Epub 2016 Sep 27. J Am Chem Soc. 2016. PMID: 27673570

4

Crystal structure of the yeast TRAPP-associated protein Tca17.

Wang C, Gohlke U, Roske Y, Heinemann U. Wang C, et al. Among authors: gohlke u. FEBS J. 2014 Sep;281(18):4195-206. doi: 10.1111/febs.12888. Epub 2014 Jul 14. FEBS J. 2014. PMID: 24961828 Free article.

5

Solvent Networks Tune Thermodynamics of Oligosaccharide Complex Formation in an Extended Protein Binding Site.

Kunstmann S, Gohlke U, Broeker NK, Roske Y, Heinemann U, Santer M, Barbirz S. Kunstmann S, et al. Among authors: gohlke u. J Am Chem Soc. 2018 Aug 22;140(33):10447-10455. doi: 10.1021/jacs.8b03719. Epub 2018 Aug 9. J Am Chem Soc. 2018. PMID: 30044908

6

Enhanced Properties of a Benzimidazole Benzylpyrazole Lysine Demethylase Inhibitor: Mechanism-of-Action, Binding Site Analysis, and Activity in Cellular Models of Prostate Cancer.

Carter DM, Specker E, Małecki PH, Przygodda J, Dudaniec K, Weiss MS, Heinemann U, Nazaré M, Gohlke U. Carter DM, et al. Among authors: gohlke u. J Med Chem. 2021 Oct 14;64(19):14266-14282. doi: 10.1021/acs.jmedchem.1c00693. Epub 2021 Sep 23. J Med Chem. 2021. PMID: 34555281 Free article.

7

Structural identification of the Vps18 β-propeller reveals a critical role in the HOPS complex stability and function.

Behrmann H, Lürick A, Kuhlee A, Balderhaar HK, Bröcker C, Kümmel D, Engelbrecht-Vandré S, Gohlke U, Raunser S, Heinemann U, Ungermann C. Behrmann H, et al. Among authors: gohlke u. J Biol Chem. 2014 Nov 28;289(48):33503-12. doi: 10.1074/jbc.M114.602714. Epub 2014 Oct 16. J Biol Chem. 2014. PMID: 25324549 Free PMC article.

8

Single amino acid exchange in bacteriophage HK620 tailspike protein results in thousand-fold increase of its oligosaccharide affinity.

Broeker NK, Gohlke U, Müller JJ, Uetrecht C, Heinemann U, Seckler R, Barbirz S. Broeker NK, et al. Among authors: gohlke u. Glycobiology. 2013 Jan;23(1):59-68. doi: 10.1093/glycob/cws126. Epub 2012 Aug 24. Glycobiology. 2013. PMID: 22923442

9

Identification of a Novel Benzimidazole Pyrazolone Scaffold That Inhibits KDM4 Lysine Demethylases and Reduces Proliferation of Prostate Cancer Cells.

Carter DM, Specker E, Przygodda J, Neuenschwander M, von Kries JP, Heinemann U, Nazaré M, Gohlke U. Carter DM, et al. Among authors: gohlke u. SLAS Discov. 2017 Aug;22(7):801-812. doi: 10.1177/2472555217699157. Epub 2017 Mar 27. SLAS Discov. 2017. PMID: 28346812 Free article.

10

Bacteriophage Tailspikes and Bacterial O-Antigens as a Model System to Study Weak-Affinity Protein-Polysaccharide Interactions.

Kang Y, Gohlke U, Engström O, Hamark C, Scheidt T, Kunstmann S, Heinemann U, Widmalm G, Santer M, Barbirz S. Kang Y, et al. Among authors: gohlke u. J Am Chem Soc. 2016 Jul 27;138(29):9109-18. doi: 10.1021/jacs.6b00240. Epub 2016 Apr 25. J Am Chem Soc. 2016. PMID: 27045683

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