Chanalaris A - Search Results

1

ADAMTS and ADAM metalloproteinases in osteoarthritis - looking beyond the 'usual suspects'.

Yang CY, Chanalaris A, Troeberg L. Yang CY, et al. Among authors: chanalaris a. Osteoarthritis Cartilage. 2017 Jul;25(7):1000-1009. doi: 10.1016/j.joca.2017.02.791. Epub 2017 Feb 13. Osteoarthritis Cartilage. 2017. PMID: 28216310 Free PMC article. Review.

2

Joint immobilization prevents murine osteoarthritis and reveals the highly mechanosensitive nature of protease expression in vivo.

Burleigh A, Chanalaris A, Gardiner MD, Driscoll C, Boruc O, Saklatvala J, Vincent TL. Burleigh A, et al. Among authors: chanalaris a. Arthritis Rheum. 2012 Jul;64(7):2278-88. doi: 10.1002/art.34420. Arthritis Rheum. 2012. PMID: 22307759 Free article.

3

Transcriptional analysis of micro-dissected articular cartilage in post-traumatic murine osteoarthritis.

Gardiner MD, Vincent TL, Driscoll C, Burleigh A, Bou-Gharios G, Saklatvala J, Nagase H, Chanalaris A. Gardiner MD, et al. Among authors: chanalaris a. Osteoarthritis Cartilage. 2015 Apr;23(4):616-28. doi: 10.1016/j.joca.2014.12.014. Epub 2014 Dec 26. Osteoarthritis Cartilage. 2015. PMID: 25545425 Free PMC article.

4

CCL2 and CCR2 regulate pain-related behaviour and early gene expression in post-traumatic murine osteoarthritis but contribute little to chondropathy.

Miotla Zarebska J, Chanalaris A, Driscoll C, Burleigh A, Miller RE, Malfait AM, Stott B, Vincent TL. Miotla Zarebska J, et al. Among authors: chanalaris a. Osteoarthritis Cartilage. 2017 Mar;25(3):406-412. doi: 10.1016/j.joca.2016.10.008. Epub 2016 Oct 13. Osteoarthritis Cartilage. 2017. PMID: 27746376 Free PMC article.

5

Suramin Inhibits Osteoarthritic Cartilage Degradation by Increasing Extracellular Levels of Chondroprotective Tissue Inhibitor of Metalloproteinases 3.

Chanalaris A, Doherty C, Marsden BD, Bambridge G, Wren SP, Nagase H, Troeberg L. Chanalaris A, et al. Mol Pharmacol. 2017 Oct;92(4):459-468. doi: 10.1124/mol.117.109397. Epub 2017 Aug 10. Mol Pharmacol. 2017. PMID: 28798097 Free PMC article.

6

Heparan Sulfate Proteoglycan Synthesis Is Dysregulated in Human Osteoarthritic Cartilage.

Chanalaris A, Clarke H, Guimond SE, Vincent TL, Turnbull JE, Troeberg L. Chanalaris A, et al. Am J Pathol. 2019 Mar;189(3):632-647. doi: 10.1016/j.ajpath.2018.11.011. Epub 2018 Dec 14. Am J Pathol. 2019. PMID: 30553836 Free article.

7

Interleukin 13 (IL-13)-regulated expression of the chondroprotective metalloproteinase ADAM15 is reduced in aging cartilage.

Yang CY, Chanalaris A, Bonelli S, McClurg O, Hiles GL, Cates AL, Zarebska JM, Vincent TL, Day ML, Müller SA, Lichtenthaler SF, Nagase H, Scilabra SD, Troeberg L. Yang CY, et al. Among authors: chanalaris a. Osteoarthr Cartil Open. 2020 Dec;2(4):100128. doi: 10.1016/j.ocarto.2020.100128. Osteoarthr Cartil Open. 2020. PMID: 33381768 Free PMC article.

8

Variants in ALDH1A2 reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis.

Zhu L, Kamalathevan P, Koneva LA, Zarebska JM, Chanalaris A, Ismail H, Wiberg A, Ng M, Muhammad H, Walsby-Tickle J, McCullagh JSO, Watt FE; Oxford Hand Surgical Team; Sansom SN, Furniss D, Gardiner MD, Vincent TL, Riley N, Spiteri M, McNab I, Little C, Cogswell L, Critchley P, Giele H, Shirley R. Zhu L, et al. Among authors: chanalaris a. Sci Transl Med. 2022 Dec 21;14(676):eabm4054. doi: 10.1126/scitranslmed.abm4054. Epub 2022 Dec 21. Sci Transl Med. 2022. PMID: 36542696

9

Fibroblast growth factor 2 drives changes in gene expression following injury to murine cartilage in vitro and in vivo.

Chong KW, Chanalaris A, Burleigh A, Jin H, Watt FE, Saklatvala J, Vincent TL. Chong KW, et al. Among authors: chanalaris a. Arthritis Rheum. 2013 Sep;65(9):2346-55. doi: 10.1002/art.38039. Arthritis Rheum. 2013. PMID: 23740825 Free PMC article.

10

Nociceptive Sensitizers Are Regulated in Damaged Joint Tissues, Including Articular Cartilage, When Osteoarthritic Mice Display Pain Behavior.

Driscoll C, Chanalaris A, Knights C, Ismail H, Sacitharan PK, Gentry C, Bevan S, Vincent TL. Driscoll C, et al. Among authors: chanalaris a. Arthritis Rheumatol. 2016 Apr;68(4):857-67. doi: 10.1002/art.39523. Arthritis Rheumatol. 2016. PMID: 26605536 Free PMC article.

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