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Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel.
Vikram A, Lewarchik CM, Yoon JY, Naqvi A, Kumar S, Morgan GM, Jacobs JS, Li Q, Kim YR, Kassan M, Liu J, Gabani M, Kumar A, Mehdi H, Zhu X, Guan X, Kutschke W, Zhang X, Boudreau RL, Dai S, Matasic DS, Jung SB, Margulies KB, Kumar V, Bachschmid MM, London B, Irani K. Vikram A, et al. Among authors: matasic ds. Nat Med. 2017 Mar;23(3):361-367. doi: 10.1038/nm.4284. Epub 2017 Feb 13. Nat Med. 2017. PMID: 28191886 Free PMC article.
Magnetic Resonance Imaging of Contracting Ultrathin Cardiac Tissue.
Shusterman V, Nagpal P, Thedens D, Zhu X, Matasic DS, Yoon JY, Morgan G, Hoffman S, London B. Shusterman V, et al. Among authors: matasic ds. Biomed Phys Eng Express. 2019 Jul;5(4):045003. doi: 10.1088/2057-1976/ab1c1c. Epub 2019 May 16. Biomed Phys Eng Express. 2019. PMID: 32733693 Free PMC article.
An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure.
Thorneloe KS, Cheung M, Bao W, Alsaid H, Lenhard S, Jian MY, Costell M, Maniscalco-Hauk K, Krawiec JA, Olzinski A, Gordon E, Lozinskaya I, Elefante L, Qin P, Matasic DS, James C, Tunstead J, Donovan B, Kallal L, Waszkiewicz A, Vaidya K, Davenport EA, Larkin J, Burgert M, Casillas LN, Marquis RW, Ye G, Eidam HS, Goodman KB, Toomey JR, Roethke TJ, Jucker BM, Schnackenberg CG, Townsley MI, Lepore JJ, Willette RN. Thorneloe KS, et al. Among authors: matasic ds. Sci Transl Med. 2012 Nov 7;4(159):159ra148. doi: 10.1126/scitranslmed.3004276. Sci Transl Med. 2012. PMID: 23136043
Cardiac Stim1 Silencing Impairs Adaptive Hypertrophy and Promotes Heart Failure Through Inactivation of mTORC2/Akt Signaling.
Bénard L, Oh JG, Cacheux M, Lee A, Nonnenmacher M, Matasic DS, Kohlbrenner E, Kho C, Pavoine C, Hajjar RJ, Hulot JS. Bénard L, et al. Among authors: matasic ds. Circulation. 2016 Apr 12;133(15):1458-71; discussion 1471. doi: 10.1161/CIRCULATIONAHA.115.020678. Epub 2016 Mar 2. Circulation. 2016. PMID: 26936863 Free PMC article.
14 results