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Page 1
Momelotinib inhibits ACVR1/ALK2, decreases hepcidin production, and ameliorates anemia of chronic disease in rodents.
Asshoff M, Petzer V, Warr MR, Haschka D, Tymoszuk P, Demetz E, Seifert M, Posch W, Nairz M, Maciejewski P, Fowles P, Burns CJ, Smith G, Wagner KU, Weiss G, Whitney JA, Theurl I. Asshoff M, et al. Among authors: wagner ku. Blood. 2017 Mar 30;129(13):1823-1830. doi: 10.1182/blood-2016-09-740092. Epub 2017 Feb 10. Blood. 2017. PMID: 28188131 Free PMC article.
RCC1 regulation of subcellular protein localization via Ran GTPase drives pancreatic ductal adenocarcinoma growth.
Bannoura SF, Aboukameel A, Khan HY, Uddin MH, Jang H, Beal EW, Thangasamy A, Shi Y, Kim S, Wagner KU, Beydoun R, El-Rayes BF, Philip PA, Mohammad RM, Saif MW, Al-Hallak MN, Pasche BC, Azmi AS. Bannoura SF, et al. Among authors: wagner ku. Cancer Lett. 2024 Nov 1;604:217275. doi: 10.1016/j.canlet.2024.217275. Epub 2024 Sep 24. Cancer Lett. 2024. PMID: 39321913
Myeloid-Specific JAK2 Contributes to Inflammation and Salt Sensitivity of Blood Pressure.
Saleem M, Aden LA, Mutchler AL, Basu C, Ertuglu LA, Sheng Q, Penner N, Hemnes AR, Park JH, Ishimwe JA, Laffer CL, Elijovich F, Wanjalla CN, de la Visitacion N, Kastner PD, Albritton CF, Ahmad T, Haynes AP, Yu J, Graber MK, Yasmin S, Wagner KU, Sayeski PP, Hatzopoulos AK, Gamazon ER, Bick AG, Kleyman TR, Kirabo A. Saleem M, et al. Among authors: wagner ku. Circ Res. 2024 Oct 11;135(9):890-909. doi: 10.1161/CIRCRESAHA.124.323595. Epub 2024 Sep 12. Circ Res. 2024. PMID: 39263750 Free article.
The Janus kinase 1 is critical for pancreatic cancer initiation and progression.
Shrestha H, Rädler PD, Dennaoui R, Wicker MN, Rajbhandari N, Sun Y, Peck AR, Vistisen K, Triplett AA, Beydoun R, Sterneck E, Saur D, Rui H, Wagner KU. Shrestha H, et al. Among authors: wagner ku. Cell Rep. 2024 May 28;43(5):114202. doi: 10.1016/j.celrep.2024.114202. Epub 2024 May 10. Cell Rep. 2024. PMID: 38733583 Free PMC article.
Regulator of Chromosome Condensation (RCC1) a novel therapeutic target in pancreatic ductal adenocarcinoma drives tumor progression via the c-Myc-RCC1-Ran axis.
Bannoura SF, Aboukameel A, Khan HY, Uddin MH, Jang H, Beal E, Thangasamy A, Kim S, Wagner KU, Mohammad R, Al-Hallak MN, Pasche BC, Azmi AS. Bannoura SF, et al. Among authors: wagner ku. bioRxiv [Preprint]. 2023 Dec 19:2023.12.18.572102. doi: 10.1101/2023.12.18.572102. bioRxiv. 2023. PMID: 38187605 Free PMC article. Preprint.
Identification of actionable targets for breast cancer intervention using a diversity outbred mouse model.
Jacob JB, Wei KC, Bepler G, Reyes JD, Cani A, Polin L, White K, Kim S, Viola N, McGrath J, Guastella A, Yin C, Mi QS, Kidder BL, Wagner KU, Ratner S, Phillips V, Xiu J, Parajuli P, Wei WZ. Jacob JB, et al. Among authors: wagner ku. iScience. 2023 Mar 2;26(4):106320. doi: 10.1016/j.isci.2023.106320. eCollection 2023 Apr 21. iScience. 2023. PMID: 36968078 Free PMC article.
145 results