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EVI2B is a C/EBPα target gene required for granulocytic differentiation and functionality of hematopoietic progenitors.
Zjablovskaja P, Kardosova M, Danek P, Angelisova P, Benoukraf T, Wurm AA, Kalina T, Sian S, Balastik M, Delwel R, Brdicka T, Tenen DG, Behre G, Fiore F, Malissen B, Horejsi V, Alberich-Jorda M. Zjablovskaja P, et al. Cell Death Differ. 2017 Apr;24(4):705-716. doi: 10.1038/cdd.2017.6. Epub 2017 Feb 10. Cell Death Differ. 2017. PMID: 28186500 Free PMC article.
The peripheral cannabinoid receptor Cb2, frequently expressed on AML blasts, either induces a neutrophilic differentiation block or confers abnormal migration properties in a ligand-dependent manner.
Alberich Jordà M, Rayman N, Tas M, Verbakel SE, Battista N, van Lom K, Löwenberg B, Maccarrone M, Delwel R. Alberich Jordà M, et al. Blood. 2004 Jul 15;104(2):526-34. doi: 10.1182/blood-2003-12-4357. Epub 2004 Mar 23. Blood. 2004. PMID: 15039279 Free article.
Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization.
Jiang S, Alberich-Jorda M, Zagozdzon R, Parmar K, Fu Y, Mauch P, Banu N, Makriyannis A, Tenen DG, Avraham S, Groopman JE, Avraham HK. Jiang S, et al. Blood. 2011 Jan 20;117(3):827-38. doi: 10.1182/blood-2010-01-265082. Epub 2010 Nov 9. Blood. 2011. Retraction in: Blood. 2011 Aug 18;118(7):2027. doi: 10.1182/blood-2011-06-363325 PMID: 21063029 Free PMC article. Retracted.
RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory element.
Levantini E, Lee S, Radomska HS, Hetherington CJ, Alberich-Jorda M, Amabile G, Zhang P, Gonzalez DA, Zhang J, Basseres DS, Wilson NK, Koschmieder S, Huang G, Zhang DE, Ebralidze AK, Bonifer C, Okuno Y, Gottgens B, Tenen DG. Levantini E, et al. EMBO J. 2011 Aug 26;30(19):4059-70. doi: 10.1038/emboj.2011.285. EMBO J. 2011. PMID: 21873977 Free PMC article.
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia.
Alberich-Jordà M, Wouters B, Balastik M, Shapiro-Koss C, Zhang H, Di Ruscio A, Radomska HS, Ebralidze AK, Amabile G, Ye M, Zhang J, Lowers I, Avellino R, Melnick A, Figueroa ME, Valk PJ, Delwel R, Tenen DG. Alberich-Jordà M, et al. J Clin Invest. 2012 Dec;122(12):4490-504. doi: 10.1172/JCI65102. Epub 2012 Nov 19. J Clin Invest. 2012. PMID: 23160200 Free PMC article.
Sustained PU.1 levels balance cell-cycle regulators to prevent exhaustion of adult hematopoietic stem cells.
Staber PB, Zhang P, Ye M, Welner RS, Nombela-Arrieta C, Bach C, Kerenyi M, Bartholdy BA, Zhang H, Alberich-Jordà M, Lee S, Yang H, Ng F, Zhang J, Leddin M, Silberstein LE, Hoefler G, Orkin SH, Göttgens B, Rosenbauer F, Huang G, Tenen DG. Staber PB, et al. Mol Cell. 2013 Mar 7;49(5):934-46. doi: 10.1016/j.molcel.2013.01.007. Epub 2013 Feb 8. Mol Cell. 2013. PMID: 23395001 Free PMC article.
48 results