Young TS - Search Results

1

Structure-Activity Relationship and Molecular Mechanics Reveal the Importance of Ring Entropy in the Biosynthesis and Activity of a Natural Product.

Tran HL, Lexa KW, Julien O, Young TS, Walsh CT, Jacobson MP, Wells JA. Tran HL, et al. Among authors: young ts. J Am Chem Soc. 2017 Feb 22;139(7):2541-2544. doi: 10.1021/jacs.6b10792. Epub 2017 Feb 13. J Am Chem Soc. 2017. PMID: 28170244 Free PMC article.

2

Generation of thiocillin ring size variants by prepeptide gene replacement and in vivo processing by Bacillus cereus.

Bowers AA, Acker MG, Young TS, Walsh CT. Bowers AA, et al. Among authors: young ts. J Am Chem Soc. 2012 Jun 27;134(25):10313-6. doi: 10.1021/ja302820x. Epub 2012 Jun 15. J Am Chem Soc. 2012. PMID: 22686940 Free PMC article.

3

Three ring posttranslational circuses: insertion of oxazoles, thiazoles, and pyridines into protein-derived frameworks.

Walsh CT, Malcolmson SJ, Young TS. Walsh CT, et al. Among authors: young ts. ACS Chem Biol. 2012 Mar 16;7(3):429-42. doi: 10.1021/cb200518n. Epub 2012 Jan 17. ACS Chem Biol. 2012. PMID: 22206579 Free PMC article.

4

The posttranslational modification cascade to the thiopeptide berninamycin generates linear forms and altered macrocyclic scaffolds.

Malcolmson SJ, Young TS, Ruby JG, Skewes-Cox P, Walsh CT. Malcolmson SJ, et al. Among authors: young ts. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8483-8. doi: 10.1073/pnas.1307111110. Epub 2013 May 6. Proc Natl Acad Sci U S A. 2013. PMID: 23650400 Free PMC article.

5

Identification of the thiazolyl peptide GE37468 gene cluster from Streptomyces ATCC 55365 and heterologous expression in Streptomyces lividans.

Young TS, Walsh CT. Young TS, et al. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13053-8. doi: 10.1073/pnas.1110435108. Epub 2011 Jul 25. Proc Natl Acad Sci U S A. 2011. PMID: 21788474 Free PMC article.

6

Codon randomization for rapid exploration of chemical space in thiopeptide antibiotic variants.

Young TS, Dorrestein PC, Walsh CT. Young TS, et al. Chem Biol. 2012 Dec 21;19(12):1600-10. doi: 10.1016/j.chembiol.2012.10.013. Chem Biol. 2012. PMID: 23261603 Free PMC article.

7

Choose Your Collimator Wisely: Inappropriate Collimator Selection During a ¹⁷⁷Lu-DOTATATE Posttreatment Scan.

Peacock JG, Young TS. Peacock JG, et al. Among authors: young ts. J Nucl Med Technol. 2024 Sep 5;52(3):274-275. doi: 10.2967/jnmt.123.266807. J Nucl Med Technol. 2024. PMID: 39237333

8

Chemoenzymatic Tagging of Tn/TF/STF Antigens in Living Systems.

Yang Y, Chen M, Wu M, Hong S, Gao B, Liu Y, Yu C, Young TS, Chapla DG, Yang JY, Cappiello JR, Li JP, Sharpless KB, Moremen KW, Wu P. Yang Y, et al. Among authors: young ts. Isr J Chem. 2023 Oct;63(10-11):e202300081. doi: 10.1002/ijch.202300081. Epub 2023 Sep 15. Isr J Chem. 2023. PMID: 38737670 Free PMC article.

9

Human CD19-specific switchable CAR T-cells are efficacious as constitutively active CAR T-cells but cause less morbidity in a mouse model of human CD19⁺ malignancy.

Pennell CA, Campbell H, Storlie MD, Bolivar-Wagers S, Osborn MJ, Refaeli Y, Jensen M, Viaud S, Young TS, Blazar BR. Pennell CA, et al. Among authors: young ts. J Immunother Cancer. 2022 Dec;10(12):e005934. doi: 10.1136/jitc-2022-005934. J Immunother Cancer. 2022. PMID: 36521930 Free PMC article.

10

JAML promotes CD8 and γδ T cell antitumor immunity and is a novel target for cancer immunotherapy.

McGraw JM, Thelen F, Hampton EN, Bruno NE, Young TS, Havran WL, Witherden DA. McGraw JM, et al. Among authors: young ts. J Exp Med. 2021 Oct 4;218(10):e20202644. doi: 10.1084/jem.20202644. Epub 2021 Aug 24. J Exp Med. 2021. PMID: 34427588 Free PMC article.

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