Phillips JA - Search Results

1

Identification of sperm mRNA biomarkers associated with testis injury during preclinical testing of pharmaceutical compounds.

Dere E, Spade DJ, Hall SJ, Altemus A, Smith JD, Phillips JA, Moffit JS, Blanchard KT, Boekelheide K. Dere E, et al. Among authors: phillips ja. Toxicol Appl Pharmacol. 2017 Apr 1;320:1-7. doi: 10.1016/j.taap.2017.02.001. Epub 2017 Feb 4. Toxicol Appl Pharmacol. 2017. PMID: 28167222

2

Assessment of inhibin B as a biomarker of testicular injury following administration of carbendazim, cetrorelix, or 1,2-dibromo-3-chloropropane in Wistar han rats.

Moffit JS, Her LS, Mineo AM, Knight BL, Phillips JA, Thibodeau MS. Moffit JS, et al. Among authors: phillips ja. Birth Defects Res B Dev Reprod Toxicol. 2013 Feb;98(1):17-28. doi: 10.1002/bdrb.21045. Epub 2013 Jan 30. Birth Defects Res B Dev Reprod Toxicol. 2013. PMID: 23364888

3

A Multiplatform Approach for the Discovery of Novel Drug-Induced Kidney Injury Biomarkers.

Chen L, Smith J, Mikl J, Fryer R, Pack F, Williams BJ, Phillips JA, Papov VV Jr. Chen L, et al. Among authors: phillips ja. Chem Res Toxicol. 2017 Oct 16;30(10):1823-1834. doi: 10.1021/acs.chemrestox.7b00159. Epub 2017 Sep 27. Chem Res Toxicol. 2017. PMID: 28885000

4

A Predominant Oxidative Renal Metabolite of Empagliflozin in Male Mice Is Cytotoxic in Mouse Renal Tubular Cells but not Genotoxic.

Smith JD, Huang Z, Escobar PA, Foppiano P, Maw H, Loging W, Yu H, Phillips JA, Taub M, Ku WW. Smith JD, et al. Among authors: phillips ja. Int J Toxicol. 2017 Nov/Dec;36(6):440-448. doi: 10.1177/1091581817735090. Epub 2017 Nov 12. Int J Toxicol. 2017. PMID: 29130831

5

Mode of action and human relevance assessment of male CD-1 mouse renal adenocarcinoma associated with lifetime exposure to empagliflozin.

Phillips JA, Taub ME, Bogdanffy MS, Yuan J, Knight B, Smith JD, Ku WW. Phillips JA, et al. J Appl Toxicol. 2022 Oct;42(10):1570-1584. doi: 10.1002/jat.4329. Epub 2022 Apr 18. J Appl Toxicol. 2022. PMID: 35393688

6

Pathogenesis of Renal Injury and Gene Expression Changes in the Male CD-1 Mouse Associated with Exposure to Empagliflozin.

Knight B, Yuan J, Koegler S, Pande P, Hall J, Hill JD, Hart SE, Phillips JA, Ku WW. Knight B, et al. Among authors: phillips ja. Toxicol Pathol. 2018 Aug;46(6):671-682. doi: 10.1177/0192623318784514. Epub 2018 Jun 26. Toxicol Pathol. 2018. PMID: 29945496

7

Rat Urinary Osteopontin and Neutrophil Gelatinase-Associated Lipocalin Improve Certainty of Detecting Drug-Induced Kidney Injury.

Phillips JA, Holder DJ, Ennulat D, Gautier JC, Sauer JM, Yang Y, McDuffie E, Sonee M, Gu YZ, Troth SP, Lynch K, Hamlin D, Peters DG, Brees D, Walker EG. Phillips JA, et al. Toxicol Sci. 2016 Jun;151(2):214-23. doi: 10.1093/toxsci/kfw038. Epub 2016 Mar 28. Toxicol Sci. 2016. PMID: 27026710

8

Net Reclassification Index and Integrated Discrimination Index Are Not Appropriate for Testing Whether a Biomarker Improves Predictive Performance.

Burch PM, Glaab WE, Holder DJ, Phillips JA, Sauer JM, Walker EG. Burch PM, et al. Among authors: phillips ja. Toxicol Sci. 2017 Mar 1;156(1):11-13. doi: 10.1093/toxsci/kfw225. Toxicol Sci. 2017. PMID: 27815493 Free PMC article.

9

Navigating tissue chips from development to dissemination: A pharmaceutical industry perspective.

Ewart L, Fabre K, Chakilam A, Dragan Y, Duignan DB, Eswaraka J, Gan J, Guzzie-Peck P, Otieno M, Jeong CG, Keller DA, de Morais SM, Phillips JA, Proctor W, Sura R, Van Vleet T, Watson D, Will Y, Tagle D, Berridge B. Ewart L, et al. Among authors: phillips ja. Exp Biol Med (Maywood). 2017 Oct;242(16):1579-1585. doi: 10.1177/1535370217715441. Epub 2017 Jun 16. Exp Biol Med (Maywood). 2017. PMID: 28622731 Free PMC article.

10

A pharmaceutical industry perspective on microphysiological kidney systems for evaluation of safety for new therapies.

Phillips JA, Grandhi TSP, Davis M, Gautier JC, Hariparsad N, Keller D, Sura R, Van Vleet TR. Phillips JA, et al. Lab Chip. 2020 Feb 7;20(3):468-476. doi: 10.1039/c9lc00925f. Epub 2020 Jan 28. Lab Chip. 2020. PMID: 31989145 Review.

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