Brion JD - Search Results

1

Design, synthesis and anticancer properties of IsoCombretaQuinolines as potent tubulin assembly inhibitors.

Khelifi I, Naret T, Renko D, Hamze A, Bernadat G, Bignon J, Lenoir C, Dubois J, Brion JD, Provot O, Alami M. Khelifi I, et al. Among authors: brion jd. Eur J Med Chem. 2017 Feb 15;127:1025-1034. doi: 10.1016/j.ejmech.2016.11.012. Epub 2016 Nov 9. Eur J Med Chem. 2017. PMID: 28166995

2

Synthesis and antitumor activity of benzils related to combretastatin A-4.

Mousset C, Giraud A, Provot O, Hamze A, Bignon J, Liu JM, Thoret S, Dubois J, Brion JD, Alami M. Mousset C, et al. Among authors: brion jd. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3266-71. doi: 10.1016/j.bmcl.2008.04.053. Epub 2008 Apr 25. Bioorg Med Chem Lett. 2008. PMID: 18477509

3

Isocombretastatins a versus combretastatins a: the forgotten isoCA-4 isomer as a highly promising cytotoxic and antitubulin agent.

Messaoudi S, Tréguier B, Hamze A, Provot O, Peyrat JF, De Losada JR, Liu JM, Bignon J, Wdzieczak-Bakala J, Thoret S, Dubois J, Brion JD, Alami M. Messaoudi S, et al. Among authors: brion jd. J Med Chem. 2009 Jul 23;52(14):4538-42. doi: 10.1021/jm900321u. J Med Chem. 2009. PMID: 19530698

4

Synthesis, biological evaluation of 1,1-diarylethylenes as a novel class of antimitotic agents.

Hamze A, Giraud A, Messaoudi S, Provot O, Peyrat JF, Bignon J, Liu JM, Wdzieczak-Bakala J, Thoret S, Dubois J, Brion JD, Alami M. Hamze A, et al. Among authors: brion jd. ChemMedChem. 2009 Nov;4(11):1912-24. doi: 10.1002/cmdc.200900290. ChemMedChem. 2009. PMID: 19790205

5

Regioselective hydrostannation of diarylalkynes directed by a labile ortho bromine atom: an easy access to stereodefined triarylolefins, hybrids of combretastatin A-4 and isocombretastatin A-4.

Rasolofonjatovo E, Provot O, Hamze A, Bignon J, Thoret S, Brion JD, Alami M. Rasolofonjatovo E, et al. Among authors: brion jd. Eur J Med Chem. 2010 Sep;45(9):3617-26. doi: 10.1016/j.ejmech.2010.05.007. Epub 2010 May 12. Eur J Med Chem. 2010. PMID: 20627378

6

Discovery of isoerianin analogues as promising anticancer agents.

Messaoudi S, Hamze A, Provot O, Tréguier B, Rodrigo De Losada J, Bignon J, Liu JM, Wdzieczak-Bakala J, Thoret S, Dubois J, Brion JD, Alami M. Messaoudi S, et al. Among authors: brion jd. ChemMedChem. 2011 Mar 7;6(3):488-97. doi: 10.1002/cmdc.201000456. Epub 2011 Jan 14. ChemMedChem. 2011. PMID: 21360820

7

B-ring-modified isocombretastatin A-4 analogues endowed with interesting anticancer activities.

Hamze A, Rasolofonjatovo E, Provot O, Mousset C, Veau D, Rodrigo J, Bignon J, Liu JM, Wdzieczak-Bakala J, Thoret S, Dubois J, Brion JD, Alami M. Hamze A, et al. Among authors: brion jd. ChemMedChem. 2011 Dec 9;6(12):2179-91. doi: 10.1002/cmdc.201100325. Epub 2011 Oct 11. ChemMedChem. 2011. PMID: 21990101

8

Conformationnally restricted naphthalene derivatives type isocombretastatin A-4 and isoerianin analogues: synthesis, cytotoxicity and antitubulin activity.

Rasolofonjatovo E, Provot O, Hamze A, Rodrigo J, Bignon J, Wdzieczak-Bakala J, Desravines D, Dubois J, Brion JD, Alami M. Rasolofonjatovo E, et al. Among authors: brion jd. Eur J Med Chem. 2012 Jun;52:22-32. doi: 10.1016/j.ejmech.2012.03.001. Epub 2012 Mar 9. Eur J Med Chem. 2012. PMID: 22449653

9

Synthesis, biological evaluation, and structure-activity relationships of tri- and tetrasubstituted olefins related to isocombretastatin A-4 as new tubulin inhibitors.

Aziz J, Brachet E, Hamze A, Peyrat JF, Bernadat G, Morvan E, Bignon J, Wdzieczak-Bakala J, Desravines D, Dubois J, Tueni M, Yassine A, Brion JD, Alami M. Aziz J, et al. Among authors: brion jd. Org Biomol Chem. 2013 Jan 21;11(3):430-42. doi: 10.1039/c2ob26253c. Epub 2012 Oct 9. Org Biomol Chem. 2013. PMID: 23047722

10

Design, synthesis and anticancer properties of 5-arylbenzoxepins as conformationally restricted isocombretastatin A-4 analogs.

Rasolofonjatovo E, Provot O, Hamze A, Rodrigo J, Bignon J, Wdzieczak-Bakala J, Lenoir C, Desravines D, Dubois J, Brion JD, Alami M. Rasolofonjatovo E, et al. Among authors: brion jd. Eur J Med Chem. 2013 Apr;62:28-39. doi: 10.1016/j.ejmech.2012.12.042. Epub 2013 Jan 4. Eur J Med Chem. 2013. PMID: 23353744

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