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Ligand and receptor dynamics contribute to the mechanism of graded PPARγ agonism.
Hughes TS, Chalmers MJ, Novick S, Kuruvilla DS, Chang MR, Kamenecka TM, Rance M, Johnson BA, Burris TP, Griffin PR, Kojetin DJ. Hughes TS, et al. Among authors: kamenecka tm. Structure. 2012 Jan 11;20(1):139-50. doi: 10.1016/j.str.2011.10.018. Structure. 2012. PMID: 22244763 Free PMC article.
Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists.
Solt LA, Wang Y, Banerjee S, Hughes T, Kojetin DJ, Lundasen T, Shin Y, Liu J, Cameron MD, Noel R, Yoo SH, Takahashi JS, Butler AA, Kamenecka TM, Burris TP. Solt LA, et al. Among authors: kamenecka tm. Nature. 2012 Mar 29;485(7396):62-8. doi: 10.1038/nature11030. Nature. 2012. PMID: 22460951 Free PMC article.
Synthesis and SAR of tetrahydroisoquinolines as Rev-erbα agonists.
Noel R, Song X, Shin Y, Banerjee S, Kojetin D, Lin L, Ruiz CH, Cameron MD, Burris TP, Kamenecka TM. Noel R, et al. Among authors: kamenecka tm. Bioorg Med Chem Lett. 2012 Jun 1;22(11):3739-42. doi: 10.1016/j.bmcl.2012.04.023. Epub 2012 Apr 13. Bioorg Med Chem Lett. 2012. PMID: 22560469 Free PMC article.
An alternate binding site for PPARγ ligands.
Hughes TS, Giri PK, de Vera IM, Marciano DP, Kuruvilla DS, Shin Y, Blayo AL, Kamenecka TM, Burris TP, Griffin PR, Kojetin DJ. Hughes TS, et al. Among authors: kamenecka tm. Nat Commun. 2014 Apr 7;5:3571. doi: 10.1038/ncomms4571. Nat Commun. 2014. PMID: 24705063 Free PMC article.
149 results