Higashitsuji H - Search Results

1

The oncoprotein gankyrin promotes the development of colitis-associated cancer through activation of STAT3.

Sakurai T, Higashitsuji H, Kashida H, Watanabe T, Komeda Y, Nagai T, Hagiwara S, Kitano M, Nishida N, Abe T, Kiyonari H, Itoh K, Fujita J, Kudo M. Sakurai T, et al. Among authors: higashitsuji h. Oncotarget. 2017 Apr 11;8(15):24762-24776. doi: 10.18632/oncotarget.14983. Oncotarget. 2017. PMID: 28160571 Free PMC article.

2

The oncoprotein gankyrin negatively regulates both p53 and RB by enhancing proteasomal degradation.

Higashitsuji H, Liu Y, Mayer RJ, Fujita J. Higashitsuji H, et al. Cell Cycle. 2005 Oct;4(10):1335-7. doi: 10.4161/cc.4.10.2107. Epub 2005 Oct 17. Cell Cycle. 2005. PMID: 16177571

3

Stress response protein cirp links inflammation and tumorigenesis in colitis-associated cancer.

Sakurai T, Kashida H, Watanabe T, Hagiwara S, Mizushima T, Iijima H, Nishida N, Higashitsuji H, Fujita J, Kudo M. Sakurai T, et al. Among authors: higashitsuji h. Cancer Res. 2014 Nov 1;74(21):6119-28. doi: 10.1158/0008-5472.CAN-14-0471. Epub 2014 Sep 3. Cancer Res. 2014. PMID: 25187386

4

MAGE-A4 interacts with the liver oncoprotein gankyrin and suppresses its tumorigenic activity.

Nagao T, Higashitsuji H, Nonoguchi K, Sakurai T, Dawson S, Mayer RJ, Itoh K, Fujita J. Nagao T, et al. Among authors: higashitsuji h. J Biol Chem. 2003 Mar 21;278(12):10668-74. doi: 10.1074/jbc.M206104200. Epub 2003 Jan 13. J Biol Chem. 2003. PMID: 12525503 Free article.

5

The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53.

Higashitsuji H, Higashitsuji H, Itoh K, Sakurai T, Nagao T, Sumitomo Y, Masuda T, Dawson S, Shimada Y, Mayer RJ, Fujita J. Higashitsuji H, et al. Cancer Cell. 2005 Jul;8(1):75-87. doi: 10.1016/j.ccr.2005.06.006. Cancer Cell. 2005. PMID: 16023600 Free article.

6

The oncoprotein gankyrin interacts with RelA and suppresses NF-kappaB activity.

Higashitsuji H, Higashitsuji H, Liu Y, Masuda T, Fujita T, Abdel-Aziz HI, Kongkham S, Dawson S, John Mayer R, Itoh Y, Sakurai T, Itoh K, Fujita J. Higashitsuji H, et al. Biochem Biophys Res Commun. 2007 Nov 23;363(3):879-84. doi: 10.1016/j.bbrc.2007.09.072. Epub 2007 Sep 29. Biochem Biophys Res Commun. 2007. PMID: 17904523

7

Gankyrin oncoprotein overexpression as a critical factor for tumor growth in human esophageal squamous cell carcinoma and its clinical significance.

Ortiz CM, Ito T, Tanaka E, Tsunoda S, Nagayama S, Sakai Y, Higashitsuji H, Fujita J, Shimada Y. Ortiz CM, et al. Among authors: higashitsuji h. Int J Cancer. 2008 Jan 15;122(2):325-32. doi: 10.1002/ijc.23106. Int J Cancer. 2008. PMID: 17935131

8

Association of gankyrin protein expression with early clinical stages and insulin-like growth factor-binding protein 5 expression in human hepatocellular carcinoma.

Umemura A, Itoh Y, Itoh K, Yamaguchi K, Nakajima T, Higashitsuji H, Onoue H, Fukumoto M, Okanoue T, Fujita J. Umemura A, et al. Among authors: higashitsuji h. Hepatology. 2008 Feb;47(2):493-502. doi: 10.1002/hep.22027. Hepatology. 2008. PMID: 18161051

9

Adriamycin enhances proteasome-mediated generation of the proapoptotic processed form of MAGE-A4 in hepatoma cells.

Sakurai T, Kudo M, Itoh K, Ryu U, Higashitsuji H, Fujita J. Sakurai T, et al. Among authors: higashitsuji h. Oncology. 2011;81 Suppl 1:30-5. doi: 10.1159/000334307. Epub 2011 Dec 22. Oncology. 2011. PMID: 22212933

10

Overexpression of gankyrin in mouse hepatocytes induces hemangioma by suppressing factor inhibiting hypoxia-inducible factor-1 (FIH-1) and activating hypoxia-inducible factor-1.

Liu Y, Higashitsuji H, Higashitsuji H, Itoh K, Sakurai T, Koike K, Hirota K, Fukumoto M, Fujita J. Liu Y, et al. Among authors: higashitsuji h. Biochem Biophys Res Commun. 2013 Mar 1;432(1):22-7. doi: 10.1016/j.bbrc.2013.01.093. Epub 2013 Feb 1. Biochem Biophys Res Commun. 2013. PMID: 23376718

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