Huang Y - Search Results

1

The discovery, complex crystal structure, and recognition mechanism of a novel natural PDE4 inhibitor from Selaginella pulvinata.

Huang Y, Liu X, Wu D, Tang G, Lai Z, Zheng X, Yin S, Luo HB. Huang Y, et al. Biochem Pharmacol. 2017 Apr 15;130:51-59. doi: 10.1016/j.bcp.2017.01.016. Epub 2017 Jan 31. Biochem Pharmacol. 2017. PMID: 28159622

2

Chemical constituents of Aloe barbadensis Miller and their inhibitory effects on phosphodiesterase-4D.

Zhong J, Huang Y, Ding W, Wu X, Wan J, Luo H. Zhong J, et al. Among authors: huang y. Fitoterapia. 2013 Dec;91:159-165. doi: 10.1016/j.fitote.2013.08.027. Epub 2013 Sep 9. Fitoterapia. 2013. PMID: 24028970

3

The molecular basis for the selectivity of tadalafil toward phosphodiesterase 5 and 6: a modeling study.

Huang YY, Li Z, Cai YH, Feng LJ, Wu Y, Li X, Luo HB. Huang YY, et al. J Chem Inf Model. 2013 Nov 25;53(11):3044-53. doi: 10.1021/ci400458z. Epub 2013 Nov 12. J Chem Inf Model. 2013. PMID: 24180640

4

Selaginpulvilins A-D, new phosphodiesterase-4 inhibitors with an unprecedented skeleton from Selaginella pulvinata.

Liu X, Luo HB, Huang YY, Bao JM, Tang GH, Chen YY, Wang J, Yin S. Liu X, et al. Org Lett. 2014 Jan 3;16(1):282-5. doi: 10.1021/ol403282f. Epub 2013 Dec 12. Org Lett. 2014. PMID: 24328835

5

Natural phosphodiesterase-4 (PDE4) inhibitors from Crotalaria ferruginea.

Liu YN, Huang YY, Bao JM, Cai YH, Guo YQ, Liu SN, Luo HB, Yin S. Liu YN, et al. Fitoterapia. 2014 Apr;94:177-82. doi: 10.1016/j.fitote.2014.02.010. Epub 2014 Mar 2. Fitoterapia. 2014. PMID: 24594242

6

Prenylated coumarins: natural phosphodiesterase-4 inhibitors from Toddalia asiatica.

Lin TT, Huang YY, Tang GH, Cheng ZB, Liu X, Luo HB, Yin S. Lin TT, et al. J Nat Prod. 2014 Apr 25;77(4):955-62. doi: 10.1021/np401040d. Epub 2014 Mar 5. J Nat Prod. 2014. PMID: 24597921

7

Natural phosphodiesterase-4 inhibitors from the leaf skin of Aloe barbadensis Miller.

Zhong JS, Huang YY, Zhang TH, Liu YP, Ding WJ, Wu XF, Xie ZY, Luo HB, Wan JZ. Zhong JS, et al. Fitoterapia. 2015 Jan;100:68-74. doi: 10.1016/j.fitote.2014.11.018. Epub 2014 Nov 28. Fitoterapia. 2015. PMID: 25449426

8

Discovery of Novel Phosphodiesterase-2A Inhibitors by Structure-Based Virtual Screening, Structural Optimization, and Bioassay.

Zhang C, Feng LJ, Huang Y, Wu D, Li Z, Zhou Q, Wu Y, Luo HB. Zhang C, et al. Among authors: huang y. J Chem Inf Model. 2017 Feb 27;57(2):355-364. doi: 10.1021/acs.jcim.6b00551. Epub 2017 Jan 18. J Chem Inf Model. 2017. PMID: 28055196

9

Bioactive triterpenoids from the leaves of Eriobotrya japonica as the natural PDE4 inhibitors.

Tan BX, Yang L, Huang YY, Chen YY, Peng GT, Yu S, Wu YN, Luo HB, He XX. Tan BX, et al. Nat Prod Res. 2017 Dec;31(24):2836-2841. doi: 10.1080/14786419.2017.1300796. Epub 2017 Mar 10. Nat Prod Res. 2017. PMID: 28281360

10

Discovery of novel purine nucleoside derivatives as phosphodiesterase 2 (PDE2) inhibitors: Structure-based virtual screening, optimization and biological evaluation.

Qiu X, Huang Y, Wu D, Mao F, Zhu J, Yan W, Luo HB, Li J. Qiu X, et al. Among authors: huang y. Bioorg Med Chem. 2018 Jan 1;26(1):119-133. doi: 10.1016/j.bmc.2017.11.022. Epub 2017 Nov 14. Bioorg Med Chem. 2018. PMID: 29174506

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