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High cholesterol level is essential for myelin membrane growth.
Saher G, Brügger B, Lappe-Siefke C, Möbius W, Tozawa R, Wehr MC, Wieland F, Ishibashi S, Nave KA. Saher G, et al. Nat Neurosci. 2005 Apr;8(4):468-75. doi: 10.1038/nn1426. Epub 2005 Mar 27. Nat Neurosci. 2005. PMID: 15793579
Ablation of cholesterol biosynthesis in neural stem cells increases their VEGF expression and angiogenesis but causes neuron apoptosis.
Saito K, Dubreuil V, Arai Y, Wilsch-Bräuninger M, Schwudke D, Saher G, Miyata T, Breier G, Thiele C, Shevchenko A, Nave KA, Huttner WB. Saito K, et al. Among authors: saher g. Proc Natl Acad Sci U S A. 2009 May 19;106(20):8350-5. doi: 10.1073/pnas.0903541106. Epub 2009 May 5. Proc Natl Acad Sci U S A. 2009. PMID: 19416849 Free PMC article.
Critical time window of neuronal cholesterol synthesis during neurite outgrowth.
Fünfschilling U, Jockusch WJ, Sivakumar N, Möbius W, Corthals K, Li S, Quintes S, Kim Y, Schaap IA, Rhee JS, Nave KA, Saher G. Fünfschilling U, et al. Among authors: saher g. J Neurosci. 2012 May 30;32(22):7632-45. doi: 10.1523/JNEUROSCI.1352-11.2012. J Neurosci. 2012. PMID: 22649242 Free PMC article.
50 results