Harp J - Search Results

1

Angptl4 does not control hyperglucagonemia or α-cell hyperplasia following glucagon receptor inhibition.

Okamoto H, Cavino K, Na E, Krumm E, Kim S, Stevis PE, Harp J, Murphy AJ, Yancopoulos GD, Gromada J. Okamoto H, et al. Among authors: harp j. Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2747-2752. doi: 10.1073/pnas.1620989114. Epub 2017 Jan 31. Proc Natl Acad Sci U S A. 2017. PMID: 28143927 Free PMC article.

2

Glucagon Receptor Blockade With a Human Antibody Normalizes Blood Glucose in Diabetic Mice and Monkeys.

Okamoto H, Kim J, Aglione J, Lee J, Cavino K, Na E, Rafique A, Kim JH, Harp J, Valenzuela DM, Yancopoulos GD, Murphy AJ, Gromada J. Okamoto H, et al. Among authors: harp j. Endocrinology. 2015 Aug;156(8):2781-94. doi: 10.1210/en.2015-1011. Epub 2015 May 28. Endocrinology. 2015. PMID: 26020795

3

A first-in-human pharmacodynamic and pharmacokinetic study of a fully human anti-glucagon receptor monoclonal antibody in normal healthy volunteers.

Kostic A, King TA, Yang F, Chan KC, Yancopoulos GD, Gromada J, Harp JB. Kostic A, et al. Among authors: harp jb. Diabetes Obes Metab. 2018 Feb;20(2):283-291. doi: 10.1111/dom.13075. Epub 2017 Sep 14. Diabetes Obes Metab. 2018. PMID: 28755409 Free PMC article. Clinical Trial.

4

Glucagon orchestrates stress-induced hyperglycaemia.

Harp JB, Yancopoulos GD, Gromada J. Harp JB, et al. Diabetes Obes Metab. 2016 Jul;18(7):648-53. doi: 10.1111/dom.12668. Epub 2016 May 4. Diabetes Obes Metab. 2016. PMID: 27027662 Free PMC article. Review.

5

Adipose-specific disruption of signal transducer and activator of transcription 3 increases body weight and adiposity.

Cernkovich ER, Deng J, Bond MC, Combs TP, Harp JB. Cernkovich ER, et al. Among authors: harp jb. Endocrinology. 2008 Apr;149(4):1581-90. doi: 10.1210/en.2007-1148. Epub 2007 Dec 20. Endocrinology. 2008. PMID: 18096662 Free PMC article.

6

A clinical trial assessing the safety and efficacy of the CB1R inverse agonist taranabant in obese and overweight patients: low-dose study.

Proietto J, Rissanen A, Harp JB, Erondu N, Yu Q, Suryawanshi S, Jones ME, Johnson-Levonas AO, Heymsfield SB, Kaufman KD, Amatruda JM. Proietto J, et al. Among authors: harp jb. Int J Obes (Lond). 2010 Aug;34(8):1243-54. doi: 10.1038/ijo.2010.38. Epub 2010 Mar 9. Int J Obes (Lond). 2010. PMID: 20212496 Clinical Trial.

7

Activation of signal transducer and activator of transcription-3 during proliferative phases of 3T3-L1 adipogenesis.

Deng J, Hua K, Lesser SS, Harp JB. Deng J, et al. Among authors: harp jb. Endocrinology. 2000 Jul;141(7):2370-6. doi: 10.1210/endo.141.7.7551. Endocrinology. 2000. PMID: 10875236

8

Interleukin-4 inhibits platelet-derived growth factor-induced preadipocyte proliferation.

Hua K, Deng J, Harp JB. Hua K, et al. Among authors: harp jb. Cytokine. 2004 Jan 21;25(2):61-7. doi: 10.1016/j.cyto.2003.09.008. Cytokine. 2004. PMID: 14693161

9

Protein inhibitor of activated STAT3 inhibits adipogenic gene expression.

Deng J, Hua K, Caveney EJ, Takahashi N, Harp JB. Deng J, et al. Among authors: harp jb. Biochem Biophys Res Commun. 2006 Jan 20;339(3):923-31. doi: 10.1016/j.bbrc.2005.10.217. Epub 2005 Nov 28. Biochem Biophys Res Commun. 2006. PMID: 16329991

10

Interleukin-4 mediates STAT6 activation in 3T3-L1 preadipocytes but not adipocytes.

Deng J, Hua K, Lesser SS, Greiner AH, Walter AW, Marrero MB, Harp JB. Deng J, et al. Among authors: harp jb. Biochem Biophys Res Commun. 2000 Jan 19;267(2):516-20. doi: 10.1006/bbrc.1999.1993. Biochem Biophys Res Commun. 2000. PMID: 10631093

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