Read C - Search Results

1

Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension.

Yang P, Read C, Kuc RE, Buonincontri G, Southwood M, Torella R, Upton PD, Crosby A, Sawiak SJ, Carpenter TA, Glen RC, Morrell NW, Maguire JJ, Davenport AP. Yang P, et al. Among authors: read c. Circulation. 2017 Mar 21;135(12):1160-1173. doi: 10.1161/CIRCULATIONAHA.116.023218. Epub 2017 Jan 30. Circulation. 2017. PMID: 28137936 Free PMC article.

2

Cardiac action of the first G protein biased small molecule apelin agonist.

Read C, Fitzpatrick CM, Yang P, Kuc RE, Maguire JJ, Glen RC, Foster RE, Davenport AP. Read C, et al. Biochem Pharmacol. 2016 Sep 15;116:63-72. doi: 10.1016/j.bcp.2016.07.018. Epub 2016 Jul 27. Biochem Pharmacol. 2016. PMID: 27475715 Free PMC article.

3

Chemerin Elicits Potent Constrictor Actions via Chemokine-Like Receptor 1 (CMKLR1), not G-Protein-Coupled Receptor 1 (GPR1), in Human and Rat Vasculature.

Kennedy AJ, Yang P, Read C, Kuc RE, Yang L, Taylor EJ, Taylor CW, Maguire JJ, Davenport AP. Kennedy AJ, et al. Among authors: read c. J Am Heart Assoc. 2016 Oct 14;5(10):e004421. doi: 10.1161/JAHA.116.004421. J Am Heart Assoc. 2016. PMID: 27742615 Free PMC article.

4

A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension.

Yang P, Read C, Kuc RE, Nyimanu D, Williams TL, Crosby A, Buonincontri G, Southwood M, Sawiak SJ, Glen RC, Morrell NW, Davenport AP, Maguire JJ. Yang P, et al. Among authors: read c. Br J Pharmacol. 2019 May;176(9):1206-1221. doi: 10.1111/bph.14603. Epub 2019 Apr 1. Br J Pharmacol. 2019. PMID: 30710493 Free PMC article.

5

Apelin peptides linked to anti-serum albumin domain antibodies retain affinity in vitro and are efficacious receptor agonists in vivo.

Read C, Yang P, Kuc RE, Nyimanu D, Williams TL, Glen RC, Holt LJ, Arulanantham H, Smart A, Davenport AP, Maguire JJ. Read C, et al. Basic Clin Pharmacol Toxicol. 2020 Jun;126 Suppl 6:96-103. doi: 10.1111/bcpt.13227. Epub 2019 Apr 10. Basic Clin Pharmacol Toxicol. 2020. PMID: 30901161 Free article.

6

International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand.

Read C, Nyimanu D, Williams TL, Huggins DJ, Sulentic P, Macrae RGC, Yang P, Glen RC, Maguire JJ, Davenport AP. Read C, et al. Pharmacol Rev. 2019 Oct;71(4):467-502. doi: 10.1124/pr.119.017533. Pharmacol Rev. 2019. PMID: 31492821 Free PMC article. Review.

7

Growth/differentiation factor 15 causes TGFβ-activated kinase 1-dependent muscle atrophy in pulmonary arterial hypertension.

Garfield BE, Crosby A, Shao D, Yang P, Read C, Sawiak S, Moore S, Parfitt L, Harries C, Rice M, Paul R, Ormiston ML, Morrell NW, Polkey MI, Wort SJ, Kemp PR. Garfield BE, et al. Among authors: read c. Thorax. 2019 Feb;74(2):164-176. doi: 10.1136/thoraxjnl-2017-211440. Epub 2018 Dec 15. Thorax. 2019. PMID: 30554141 Free PMC article. Clinical Trial.

8

The G Protein Biased Small Molecule Apelin Agonist CMF-019 is Disease Modifying in Endothelial Cell Apoptosis In Vitro and Induces Vasodilatation Without Desensitisation In Vivo.

Read C, Nyimanu D, Yang P, Kuc RE, Williams TL, Fitzpatrick CM, Foster R, Glen RC, Maguire JJ, Davenport AP. Read C, et al. Front Pharmacol. 2021 Jan 21;11:588669. doi: 10.3389/fphar.2020.588669. eCollection 2020. Front Pharmacol. 2021. PMID: 33716722 Free PMC article.

9

G protein signaling-biased mu opioid receptor agonists that produce sustained G protein activation are noncompetitive agonists.

Stahl EL, Schmid CL, Acevedo-Canabal A, Read C, Grim TW, Kennedy NM, Bannister TD, Bohn LM. Stahl EL, et al. Among authors: read c. Proc Natl Acad Sci U S A. 2021 Nov 30;118(48):e2102178118. doi: 10.1073/pnas.2102178118. Proc Natl Acad Sci U S A. 2021. PMID: 34819362 Free PMC article.

10

[No title available]

[No authors listed] [No authors listed] PMID: 35552911

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