Thomas SE - Search Results

1

Structure-guided, target-based drug discovery - exploiting genome information from HIV to mycobacterial infections.

Malhotra S, Thomas SE, Ochoa Montano B, Blundell TL. Malhotra S, et al. Among authors: thomas se. Postepy Biochem. 2016;62(3):262-272. Postepy Biochem. 2016. PMID: 28132480 Review. English.

2

Structural insights into the EthR-DNA interaction using native mass spectrometry.

Shiu-Hin Chan D, Seetoh WG, McConnell BN, Matak-Vinković D, Thomas SE, Mendes V, Blaszczyk M, Coyne AG, Blundell TL, Abell C. Shiu-Hin Chan D, et al. Among authors: thomas se. Chem Commun (Camb). 2017 Mar 23;53(25):3527-3530. doi: 10.1039/c7cc00804j. Chem Commun (Camb). 2017. PMID: 28287239 Free PMC article.

3

Genomes, structural biology and drug discovery: combating the impacts of mutations in genetic disease and antibiotic resistance.

Pandurangan AP, Ascher DB, Thomas SE, Blundell TL. Pandurangan AP, et al. Among authors: thomas se. Biochem Soc Trans. 2017 Apr 15;45(2):303-311. doi: 10.1042/BST20160422. Biochem Soc Trans. 2017. PMID: 28408471 Free PMC article. Review.

4

Fragment Screening against the EthR-DNA Interaction by Native Mass Spectrometry.

Chan DS, Mendes V, Thomas SE, McConnell BN, Matak-Vinković D, Coyne AG, Blundell TL, Abell C. Chan DS, et al. Among authors: thomas se. Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7488-7491. doi: 10.1002/anie.201702888. Epub 2017 May 31. Angew Chem Int Ed Engl. 2017. PMID: 28513917

5

Structural Biology and the Design of New Therapeutics: From HIV and Cancer to Mycobacterial Infections: A Paper Dedicated to John Kendrew.

Thomas SE, Mendes V, Kim SY, Malhotra S, Ochoa-Montaño B, Blaszczyk M, Blundell TL. Thomas SE, et al. J Mol Biol. 2017 Aug 18;429(17):2677-2693. doi: 10.1016/j.jmb.2017.06.014. Epub 2017 Jun 23. J Mol Biol. 2017. PMID: 28648615 Free article. Review.

6

Arginine-deprivation-induced oxidative damage sterilizes Mycobacterium tuberculosis.

Tiwari S, van Tonder AJ, Vilchèze C, Mendes V, Thomas SE, Malek A, Chen B, Chen M, Kim J, Blundell TL, Parkhill J, Weinrick B, Berney M, Jacobs WR Jr. Tiwari S, et al. Among authors: thomas se. Proc Natl Acad Sci U S A. 2018 Sep 25;115(39):9779-9784. doi: 10.1073/pnas.1808874115. Epub 2018 Aug 24. Proc Natl Acad Sci U S A. 2018. PMID: 30143580 Free PMC article.

7

Mycobacterial genomics and structural bioinformatics: opportunities and challenges in drug discovery.

Waman VP, Vedithi SC, Thomas SE, Bannerman BP, Munir A, Skwark MJ, Malhotra S, Blundell TL. Waman VP, et al. Among authors: thomas se. Emerg Microbes Infect. 2019;8(1):109-118. doi: 10.1080/22221751.2018.1561158. Emerg Microbes Infect. 2019. PMID: 30866765 Free PMC article. Review.

8

Structure-guided fragment-based drug discovery at the synchrotron: screening binding sites and correlations with hotspot mapping.

Thomas SE, Collins P, James RH, Mendes V, Charoensutthivarakul S, Radoux C, Abell C, Coyne AG, Floto RA, von Delft F, Blundell TL. Thomas SE, et al. Philos Trans A Math Phys Eng Sci. 2019 Jun 17;377(2147):20180422. doi: 10.1098/rsta.2018.0422. Philos Trans A Math Phys Eng Sci. 2019. PMID: 31030650 Free PMC article.

9

Development of Inhibitors against Mycobacterium abscessus tRNA (m¹G37) Methyltransferase (TrmD) Using Fragment-Based Approaches.

Whitehouse AJ, Thomas SE, Brown KP, Fanourakis A, Chan DS, Libardo MDJ, Mendes V, Boshoff HIM, Floto RA, Abell C, Blundell TL, Coyne AG. Whitehouse AJ, et al. Among authors: thomas se. J Med Chem. 2019 Aug 8;62(15):7210-7232. doi: 10.1021/acs.jmedchem.9b00809. Epub 2019 Jul 19. J Med Chem. 2019. PMID: 31282680 Free PMC article.

10

Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification.

Thomas SE, Whitehouse AJ, Brown K, Burbaud S, Belardinelli JM, Sangen J, Lahiri R, Libardo MDJ, Gupta P, Malhotra S, Boshoff HIM, Jackson M, Abell C, Coyne AG, Blundell TL, Floto RA, Mendes V. Thomas SE, et al. Nucleic Acids Res. 2020 Aug 20;48(14):8099-8112. doi: 10.1093/nar/gkaa539. Nucleic Acids Res. 2020. PMID: 32602532 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

209 results

Search Page

Filters