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Transcriptome analysis reveals a dynamic and differential transcriptional response to sulforaphane in normal and prostate cancer cells and suggests a role for Sp1 in chemoprevention.
Beaver LM, Buchanan A, Sokolowski EI, Riscoe AN, Wong CP, Chang JH, Löhr CV, Williams DE, Dashwood RH, Ho E. Beaver LM, et al. Among authors: williams de. Mol Nutr Food Res. 2014 Oct;58(10):2001-13. doi: 10.1002/mnfr.201400269. Epub 2014 Aug 5. Mol Nutr Food Res. 2014. PMID: 25044704 Free PMC article.
The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.
Palomera-Sanchez Z, Watson GW, Wong CP, Beaver LM, Williams DE, Dashwood RH, Ho E. Palomera-Sanchez Z, et al. Among authors: williams de. J Nutr Biochem. 2017 Sep;47:113-119. doi: 10.1016/j.jnutbio.2017.05.005. Epub 2017 May 25. J Nutr Biochem. 2017. PMID: 28582660 Free PMC article.
Sulforaphane Bioavailability and Chemopreventive Activity in Men Presenting for Biopsy of the Prostate Gland: A Randomized Controlled Trial.
Zhang Z, Garzotto M, Davis EW 2nd, Mori M, Stoller WA, Farris PE, Wong CP, Beaver LM, Thomas GV, Williams DE, Dashwood RH, Hendrix DA, Ho E, Shannon J. Zhang Z, et al. Among authors: williams de. Nutr Cancer. 2020;72(1):74-87. doi: 10.1080/01635581.2019.1619783. Epub 2019 Jun 1. Nutr Cancer. 2020. PMID: 31155953 Free PMC article. Clinical Trial.
936 results