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Melatonin-micronutrients Osteopenia Treatment Study (MOTS): a translational study assessing melatonin, strontium (citrate), vitamin D3 and vitamin K2 (MK7) on bone density, bone marker turnover and health related quality of life in postmenopausal osteopenic women following a one-year double-blind RCT and on osteoblast-osteoclast co-cultures.
Maria S, Swanson MH, Enderby LT, D'Amico F, Enderby B, Samsonraj RM, Dudakovic A, van Wijnen AJ, Witt-Enderby PA. Maria S, et al. Among authors: samsonraj rm. Aging (Albany NY). 2017 Jan 26;9(1):256-285. doi: 10.18632/aging.101158. Aging (Albany NY). 2017. PMID: 28130552 Free PMC article.
Biological effects of melatonin on osteoblast/osteoclast cocultures, bone, and quality of life: Implications of a role for MT2 melatonin receptors, MEK1/2, and MEK5 in melatonin-mediated osteoblastogenesis.
Maria S, Samsonraj RM, Munmun F, Glas J, Silvestros M, Kotlarczyk MP, Rylands R, Dudakovic A, van Wijnen AJ, Enderby LT, Lassila H, Dodda B, Davis VL, Balk J, Burow M, Bunnell BA, Witt-Enderby PA. Maria S, et al. Among authors: samsonraj rm. J Pineal Res. 2018 Apr;64(3):10.1111/jpi.12465. doi: 10.1111/jpi.12465. Epub 2018 Jan 17. J Pineal Res. 2018. PMID: 29285799 Free PMC article.
Inhibition of the epigenetic suppressor EZH2 primes osteogenic differentiation mediated by BMP2.
Dudakovic A, Samsonraj RM, Paradise CR, Galeano-Garces C, Mol MO, Galeano-Garces D, Zan P, Galvan ML, Hevesi M, Pichurin O, Thaler R, Begun DL, Kloen P, Karperien M, Larson AN, Westendorf JJ, Cool SM, van Wijnen AJ. Dudakovic A, et al. Among authors: samsonraj rm. J Biol Chem. 2020 Jun 5;295(23):7877-7893. doi: 10.1074/jbc.RA119.011685. Epub 2020 Apr 24. J Biol Chem. 2020. PMID: 32332097 Free PMC article.
27 results