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Molecular dissection of germline chromothripsis in a developmental context using patient-derived iPS cells.
Middelkamp S, van Heesch S, Braat AK, de Ligt J, van Iterson M, Simonis M, van Roosmalen MJ, Kelder MJ, Kruisselbrink E, Hochstenbach R, Verbeek NE, Ippel EF, Adolfs Y, Pasterkamp RJ, Kloosterman WP, Kuijk EW, Cuppen E. Middelkamp S, et al. Among authors: adolfs y. Genome Med. 2017 Jan 26;9(1):9. doi: 10.1186/s13073-017-0399-z. Genome Med. 2017. PMID: 28126037 Free PMC article.
Semaphorin 3F is a bifunctional guidance cue for dopaminergic axons and controls their fasciculation, channeling, rostral growth, and intracortical targeting.
Kolk SM, Gunput RA, Tran TS, van den Heuvel DM, Prasad AA, Hellemons AJ, Adolfs Y, Ginty DD, Kolodkin AL, Burbach JP, Smidt MP, Pasterkamp RJ. Kolk SM, et al. Among authors: adolfs y. J Neurosci. 2009 Oct 7;29(40):12542-57. doi: 10.1523/JNEUROSCI.2521-09.2009. J Neurosci. 2009. PMID: 19812329 Free PMC article.
MICAL-1 is a negative regulator of MST-NDR kinase signaling and apoptosis.
Zhou Y, Adolfs Y, Pijnappel WW, Fuller SJ, Van der Schors RC, Li KW, Sugden PH, Smit AB, Hergovich A, Pasterkamp RJ. Zhou Y, et al. Among authors: adolfs y. Mol Cell Biol. 2011 Sep;31(17):3603-15. doi: 10.1128/MCB.01389-10. Epub 2011 Jul 5. Mol Cell Biol. 2011. PMID: 21730291 Free PMC article.
MICALs in control of the cytoskeleton, exocytosis, and cell death.
Zhou Y, Gunput RA, Adolfs Y, Pasterkamp RJ. Zhou Y, et al. Among authors: adolfs y. Cell Mol Life Sci. 2011 Dec;68(24):4033-44. doi: 10.1007/s00018-011-0787-2. Epub 2011 Aug 6. Cell Mol Life Sci. 2011. PMID: 21822644 Free PMC article. Review.
Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases.
van Erp S, van den Heuvel DMA, Fujita Y, Robinson RA, Hellemons AJCGM, Adolfs Y, Van Battum EY, Blokhuis AM, Kuijpers M, Demmers JAA, Hedman H, Hoogenraad CC, Siebold C, Yamashita T, Pasterkamp RJ. van Erp S, et al. Among authors: adolfs y. Dev Cell. 2015 Dec 7;35(5):537-552. doi: 10.1016/j.devcel.2015.11.008. Dev Cell. 2015. PMID: 26651291 Free article.
31 results