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The mouse mutation "thrombocytopenia and cardiomyopathy" (trac) disrupts Abcg5: a spontaneous single gene model for human hereditary phytosterolemia/sitosterolemia.
Chase TH, Lyons BL, Bronson RT, Foreman O, Donahue LR, Burzenski LM, Gott B, Lane P, Harris B, Ceglarek U, Thiery J, Wittenburg H, Thon JN, Italiano JE Jr, Johnson KR, Shultz LD. Chase TH, et al. Among authors: shultz ld. Blood. 2010 Feb 11;115(6):1267-76. doi: 10.1182/blood-2009-05-219808. Epub 2009 Oct 21. Blood. 2010. PMID: 19846887 Free PMC article.
Human cancer growth and therapy in immunodeficient mouse models.
Shultz LD, Goodwin N, Ishikawa F, Hosur V, Lyons BL, Greiner DL. Shultz LD, et al. Cold Spring Harb Protoc. 2014 Jul 1;2014(7):694-708. doi: 10.1101/pdb.top073585. Cold Spring Harb Protoc. 2014. PMID: 24987146 Free PMC article. Review.
Patient-Derived Tumor Xenografts: Why Now?
Liu ET, Bult CJ, Shultz LD. Liu ET, et al. JAMA Oncol. 2016 May 1;2(5):567-568. doi: 10.1001/jamaoncol.2016.0193. JAMA Oncol. 2016. PMID: 27055176 No abstract available.
SVEP1 plays a crucial role in epidermal differentiation.
Samuelov L, Li Q, Bochner R, Najor NA, Albrecht L, Malchin N, Goldsmith T, Grafi-Cohen M, Vodo D, Fainberg G, Meilik B, Goldberg I, Warshauer E, Rogers T, Edie S, Ishida-Yamamoto A, Burzenski L, Erez N, Murray SA, Irvine AD, Shultz L, Green KJ, Uitto J, Sprecher E, Sarig O. Samuelov L, et al. Among authors: shultz l. Exp Dermatol. 2017 May;26(5):423-430. doi: 10.1111/exd.13256. Epub 2017 Feb 20. Exp Dermatol. 2017. PMID: 27892606 Free PMC article.
Development of Humanized Mice in the Age of Genome Editing.
Hosur V, Low BE, Avery C, Shultz LD, Wiles MV. Hosur V, et al. J Cell Biochem. 2017 Oct;118(10):3043-3048. doi: 10.1002/jcb.26002. Epub 2017 May 15. J Cell Biochem. 2017. PMID: 28332231 Free PMC article.
Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics.
Kooreman NG, de Almeida PE, Stack JP, Nelakanti RV, Diecke S, Shao NY, Swijnenburg RJ, Sanchez-Freire V, Matsa E, Liu C, Connolly AJ, Hamming JF, Quax PHA, Brehm MA, Greiner DL, Shultz LD, Wu JC. Kooreman NG, et al. Among authors: shultz ld. Cell Rep. 2017 Aug 22;20(8):1978-1990. doi: 10.1016/j.celrep.2017.08.003. Cell Rep. 2017. PMID: 28834758 Free PMC article.
Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy.
Wang M, Yao LC, Cheng M, Cai D, Martinek J, Pan CX, Shi W, Ma AH, De Vere White RW, Airhart S, Liu ET, Banchereau J, Brehm MA, Greiner DL, Shultz LD, Palucka K, Keck JG. Wang M, et al. Among authors: shultz ld. FASEB J. 2018 Mar;32(3):1537-1549. doi: 10.1096/fj.201700740R. Epub 2018 Jan 3. FASEB J. 2018. PMID: 29146734 Free PMC article.
Thus, tumor-bearing HuNSG mice may represent an important, new model for preclinical immunotherapy research.-Wang, M., Yao, L.-C., Cheng, M., Cai, D., Martinek, J., Pan, C.-X., Shi, W., Ma, A.-H., De Vere White, R. ...T., Banchereau, J., Brehm, M. A., Greiner, D. L. …
Thus, tumor-bearing HuNSG mice may represent an important, new model for preclinical immunotherapy research.-Wang, M., Yao, L.-C., Ch …
534 results