Yuan S - Search Results

1

PAN substitutions A37S, A37S/I61T and A37S/V63I attenuate the replication of H7N7 influenza A virus by impairing the polymerase and endonuclease activities.

Hu M, Yuan S, Ye ZW, Singh K, Li C, Shuai H, Fai N, Chow BKC, Chu H, Zheng BJ. Hu M, et al. Among authors: yuan s. J Gen Virol. 2017 Mar;98(3):364-373. doi: 10.1099/jgv.0.000717. Epub 2017 Apr 1. J Gen Virol. 2017. PMID: 28113045

2

Comparative immunological evaluation of recombinant Salmonella Typhimurium strains expressing model antigens as live oral vaccines.

Zheng SY, Yu B, Zhang K, Chen M, Hua YH, Yuan S, Watt RM, Zheng BJ, Yuen KY, Huang JD. Zheng SY, et al. Among authors: yuan s. BMC Immunol. 2012 Sep 26;13:54. doi: 10.1186/1471-2172-13-54. BMC Immunol. 2012. PMID: 23013063 Free PMC article.

3

Cross-protection of influenza A virus infection by a DNA aptamer targeting the PA endonuclease domain.

Yuan S, Zhang N, Singh K, Shuai H, Chu H, Zhou J, Chow BK, Zheng BJ. Yuan S, et al. Antimicrob Agents Chemother. 2015 Jul;59(7):4082-93. doi: 10.1128/AAC.00306-15. Epub 2015 Apr 27. Antimicrob Agents Chemother. 2015. PMID: 25918143 Free PMC article.

4

Identification of a small-molecule inhibitor of influenza virus via disrupting the subunits interaction of the viral polymerase.

Yuan S, Chu H, Zhao H, Zhang K, Singh K, Chow BK, Kao RY, Zhou J, Zheng BJ. Yuan S, et al. Antiviral Res. 2016 Jan;125:34-42. doi: 10.1016/j.antiviral.2015.11.005. Epub 2015 Nov 22. Antiviral Res. 2016. PMID: 26593979

5

A novel small-molecule inhibitor of influenza A virus acts by suppressing PA endonuclease activity of the viral polymerase.

Yuan S, Chu H, Singh K, Zhao H, Zhang K, Kao RY, Chow BK, Zhou J, Zheng BJ. Yuan S, et al. Sci Rep. 2016 Mar 9;6:22880. doi: 10.1038/srep22880. Sci Rep. 2016. PMID: 26956222 Free PMC article.

6

A novel small-molecule compound disrupts influenza A virus PB2 cap-binding and inhibits viral replication.

Yuan S, Chu H, Zhang K, Ye J, Singh K, Kao RY, Chow BK, Zhou J, Zheng BJ. Yuan S, et al. J Antimicrob Chemother. 2016 Sep;71(9):2489-97. doi: 10.1093/jac/dkw194. Epub 2016 Jun 5. J Antimicrob Chemother. 2016. PMID: 27272726

7

Novel residues in the PA protein of avian influenza H7N7 virus affect virulence in mammalian hosts.

Zhao H, Chu H, Zhao X, Shuai H, Wong BH, Wen L, Yuan S, Zheng BJ, Zhou J, Yuen KY. Zhao H, et al. Among authors: yuan s. Virology. 2016 Nov;498:1-8. doi: 10.1016/j.virol.2016.08.004. Epub 2016 Aug 12. Virology. 2016. PMID: 27525812 Free article.

8

Peptide-Mediated Interference of PB2-eIF4G1 Interaction Inhibits Influenza A Viruses' Replication in Vitro and in Vivo.

Yuan S, Chu H, Ye J, Hu M, Singh K, Chow BK, Zhou J, Zheng BJ. Yuan S, et al. ACS Infect Dis. 2016 Jul 8;2(7):471-7. doi: 10.1021/acsinfecdis.6b00064. Epub 2016 Jun 13. ACS Infect Dis. 2016. PMID: 27626099

9

Identification of a novel small-molecule compound targeting the influenza A virus polymerase PB1-PB2 interface.

Yuan S, Chu H, Ye J, Singh K, Ye Z, Zhao H, Kao RY, Chow BK, Zhou J, Zheng BJ. Yuan S, et al. Antiviral Res. 2017 Jan;137:58-66. doi: 10.1016/j.antiviral.2016.11.005. Epub 2016 Nov 10. Antiviral Res. 2017. PMID: 27840201 Free PMC article.

10

Amino acid substitutions V63I or A37S/I61T/V63I/V100A in the PA N-terminal domain increase the virulence of H7N7 influenza A virus.

Hu M, Chu H, Zhang K, Singh K, Li C, Yuan S, Chow BK, Song W, Zhou J, Zheng BJ. Hu M, et al. Among authors: yuan s. Sci Rep. 2016 Nov 25;6:37800. doi: 10.1038/srep37800. Sci Rep. 2016. PMID: 27886255 Free PMC article.

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