Trapani JA - Search Results

1

Benzenesulphonamide inhibitors of the cytolytic protein perforin.

Spicer JA, Miller CK, O'Connor PD, Jose J, Huttunen KM, Jaiswal JK, Denny WA, Akhlaghi H, Browne KA, Trapani JA. Spicer JA, et al. Among authors: trapani ja. Bioorg Med Chem Lett. 2017 Feb 15;27(4):1050-1054. doi: 10.1016/j.bmcl.2016.12.057. Epub 2016 Dec 23. Bioorg Med Chem Lett. 2017. PMID: 28110869 Free PMC article.

2

Distinct granzyme expression in human CD3- CD56+ large granular- and CD3- CD56+ small high density-lymphocytes displaying non-MHC-restricted cytolytic activity.

Smyth MJ, Browne KA, Kinnear BF, Trapani JA, Warren HS. Smyth MJ, et al. Among authors: trapani ja. J Leukoc Biol. 1995 Jan;57(1):88-93. doi: 10.1002/jlb.57.1.88. J Leukoc Biol. 1995. PMID: 7530284

3

The peptide loop consisting of amino acids 139-157 of human granzyme B (fragmentin 2) contains an immunodominant epitope recognized by the mouse.

Apostolidis VA, Browne KA, Smyth MJ, Trapani JA. Apostolidis VA, et al. Among authors: trapani ja. Mol Immunol. 1995 Aug;32(12):909-17. doi: 10.1016/0161-5890(95)00042-d. Mol Immunol. 1995. PMID: 7565817

4

Genomic organization of IFI16, an interferon-inducible gene whose expression is associated with human myeloid cell differentiation: correlation of predicted protein domains with exon organization.

Trapani JA, Dawson M, Apostolidis VA, Browne KA. Trapani JA, et al. Immunogenetics. 1994;40(6):415-24. doi: 10.1007/BF00177824. Immunogenetics. 1994. PMID: 7959953

5

Granule serine proteases are normal nuclear constituents of natural killer cells.

Trapani JA, Smyth MJ, Apostolidis VA, Dawson M, Browne KA. Trapani JA, et al. J Biol Chem. 1994 Jul 15;269(28):18359-65. J Biol Chem. 1994. PMID: 8034581 Free article.

6

Hypothesis: cytotoxic lymphocyte granule serine proteases activate target cell endonucleases to trigger apoptosis.

Smyth MJ, Browne KA, Thia KY, Apostolidis VA, Kershaw MH, Trapani JA. Smyth MJ, et al. Among authors: trapani ja. Clin Exp Pharmacol Physiol. 1994 Jan;21(1):67-70. doi: 10.1111/j.1440-1681.1994.tb02438.x. Clin Exp Pharmacol Physiol. 1994. PMID: 8156655

7

Immunopurification of functional Asp-ase (natural killer cell granzyme B) using a monoclonal antibody.

Trapani JA, Browne KA, Dawson M, Smyth MJ. Trapani JA, et al. Biochem Biophys Res Commun. 1993 Sep 15;195(2):910-20. doi: 10.1006/bbrc.1993.2131. Biochem Biophys Res Commun. 1993. PMID: 8373425

8

Localization of granzyme B in the nucleus. A putative role in the mechanism of cytotoxic lymphocyte-mediated apoptosis.

Trapani JA, Browne KA, Smyth MJ, Jans DA. Trapani JA, et al. J Biol Chem. 1996 Feb 23;271(8):4127-33. doi: 10.1074/jbc.271.8.4127. J Biol Chem. 1996. PMID: 8626751 Free article.

9

Efficient nuclear targeting of granzyme B and the nuclear consequences of apoptosis induced by granzyme B and perforin are caspase-dependent, but cell death is caspase-independent.

Trapani JA, Jans DA, Jans PJ, Smyth MJ, Browne KA, Sutton VR. Trapani JA, et al. J Biol Chem. 1998 Oct 23;273(43):27934-8. doi: 10.1074/jbc.273.43.27934. J Biol Chem. 1998. PMID: 9774406 Free article.

10

Anti-viral strategies of cytotoxic T lymphocytes are manifested through a variety of granule-bound pathways of apoptosis induction.

Edwards KM, Davis JE, Browne KA, Sutton VR, Trapani JA. Edwards KM, et al. Among authors: trapani ja. Immunol Cell Biol. 1999 Feb;77(1):76-89. doi: 10.1046/j.1440-1711.1999.00799.x. Immunol Cell Biol. 1999. PMID: 10101689 Review.

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