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The TOMM40 poly-T rs10524523 variant is associated with cognitive performance among non-demented elderly with type 2 diabetes.
Greenbaum L, Springer RR, Lutz MW, Heymann A, Lubitz I, Cooper I, Kravitz E, Sano M, Roses AD, Silverman JM, Saunders AM, Beeri MS. Greenbaum L, et al. Among authors: saunders am. Eur Neuropsychopharmacol. 2014 Sep;24(9):1492-9. doi: 10.1016/j.euroneuro.2014.06.002. Epub 2014 Jun 13. Eur Neuropsychopharmacol. 2014. PMID: 25044051 Free PMC article.
African-American TOMM40'523-APOE haplotypes are admixture of West African and Caucasian alleles.
Roses AD, Lutz MW, Saunders AM, Goldgaber D, Saul R, Sundseth SS, Akkari PA, Roses SM, Gottschalk WK, Whitfield KE, Vostrov AA, Hauser MA, Allingham RR, Burns DK, Chiba-Falek O, Welsh-Bohmer KA. Roses AD, et al. Among authors: saunders am. Alzheimers Dement. 2014 Nov;10(6):592-601.e2. doi: 10.1016/j.jalz.2014.06.009. Epub 2014 Sep 26. Alzheimers Dement. 2014. PMID: 25260913 Free article.
Neuropathologic features of TOMM40 '523 variant on late-life cognitive decline.
Yu L, Lutz MW, Farfel JM, Wilson RS, Burns DK, Saunders AM, De Jager PL, Barnes LL, Schneider JA, Bennett DA. Yu L, et al. Among authors: saunders am. Alzheimers Dement. 2017 Dec;13(12):1380-1388. doi: 10.1016/j.jalz.2017.05.002. Epub 2017 Jun 15. Alzheimers Dement. 2017. PMID: 28624335 Free PMC article.
Genetic variation at a single locus and age of onset for Alzheimer's disease.
Lutz MW, Crenshaw DG, Saunders AM, Roses AD. Lutz MW, et al. Among authors: saunders am. Alzheimers Dement. 2010 Mar;6(2):125-31. doi: 10.1016/j.jalz.2010.01.011. Alzheimers Dement. 2010. PMID: 20298972 Free PMC article.
The significant finding discussed here is that a variable-length, deoxythymidine homopolymer (poly-T) within intron 6 of the TOMM40 gene is associated with the age of onset of LOAD [Roses AD, Lutz MW, Amrine-Madsen H, Saunders AM, Crenshaw DG, Sundseth SS, et al. A …
The significant finding discussed here is that a variable-length, deoxythymidine homopolymer (poly-T) within intron 6 of the TOMM40 gene is …
The importance of being connected.
Lutz MW, Crenshaw DG, Saunders AM, Roses AD. Lutz MW, et al. Among authors: saunders am. J Alzheimers Dis. 2011;24(2):247-51. doi: 10.3233/JAD-2010-101765. J Alzheimers Dis. 2011. PMID: 21206004 Free article. No abstract available.
284 results