Grollman A - Search Results

1

DNA Deformation-Coupled Recognition of 8-Oxoguanine: Conformational Kinetic Gating in Human DNA Glycosylase.

Li H, Endutkin AV, Bergonzo C, Fu L, Grollman A, Zharkov DO, Simmerling C. Li H, et al. Among authors: grollman a. J Am Chem Soc. 2017 Feb 22;139(7):2682-2692. doi: 10.1021/jacs.6b11433. Epub 2017 Feb 8. J Am Chem Soc. 2017. PMID: 28098999 Free PMC article.

2

A dynamic checkpoint in oxidative lesion discrimination by formamidopyrimidine-DNA glycosylase.

Li H, Endutkin AV, Bergonzo C, Campbell AJ, de los Santos C, Grollman A, Zharkov DO, Simmerling C. Li H, et al. Among authors: grollman a. Nucleic Acids Res. 2016 Jan 29;44(2):683-94. doi: 10.1093/nar/gkv1092. Epub 2015 Nov 8. Nucleic Acids Res. 2016. PMID: 26553802 Free PMC article.

3

The DNA trackwalkers: principles of lesion search and recognition by DNA glycosylases.

Zharkov DO, Grollman AP. Zharkov DO, et al. Mutat Res. 2005 Sep 4;577(1-2):24-54. doi: 10.1016/j.mrfmmm.2005.03.011. Mutat Res. 2005. PMID: 15939442 Review.

4

Molecular simulations reveal a common binding mode for glycosylase binding of oxidatively damaged DNA lesions.

Song K, Kelso C, de los Santos C, Grollman AP, Simmerling C. Song K, et al. J Am Chem Soc. 2007 Nov 28;129(47):14536-7. doi: 10.1021/ja075128w. Epub 2007 Nov 8. J Am Chem Soc. 2007. PMID: 17988127 Free PMC article.

5

Substrate specificity and excision kinetics of natural polymorphic variants and phosphomimetic mutants of human 8-oxoguanine-DNA glycosylase.

Sidorenko VS, Grollman AP, Jaruga P, Dizdaroglu M, Zharkov DO. Sidorenko VS, et al. FEBS J. 2009 Sep;276(18):5149-62. doi: 10.1111/j.1742-4658.2009.07212.x. Epub 2009 Aug 7. FEBS J. 2009. PMID: 19674107 Free PMC article.

6

Energetic preference of 8-oxoG eversion pathways in a DNA glycosylase.

Bergonzo C, Campbell AJ, de los Santos C, Grollman AP, Simmerling C. Bergonzo C, et al. J Am Chem Soc. 2011 Sep 21;133(37):14504-6. doi: 10.1021/ja205142d. Epub 2011 Aug 25. J Am Chem Soc. 2011. PMID: 21848286 Free PMC article.

7

Active destabilization of base pairs by a DNA glycosylase wedge initiates damage recognition.

Kuznetsov NA, Bergonzo C, Campbell AJ, Li H, Mechetin GV, de los Santos C, Grollman AP, Fedorova OS, Zharkov DO, Simmerling C. Kuznetsov NA, et al. Among authors: grollman ap. Nucleic Acids Res. 2015 Jan;43(1):272-81. doi: 10.1093/nar/gku1300. Epub 2014 Dec 17. Nucleic Acids Res. 2015. PMID: 25520195 Free PMC article.

8

Dynamic behavior of DNA base pairs containing 8-oxoguanine.

Cheng X, Kelso C, Hornak V, de los Santos C, Grollman AP, Simmerling C. Cheng X, et al. J Am Chem Soc. 2005 Oct 12;127(40):13906-18. doi: 10.1021/ja052542s. J Am Chem Soc. 2005. PMID: 16201812 Free PMC article.

9

Combining structural and bioinformatics methods for the analysis of functionally important residues in DNA glycosylases.

Zharkov DO, Grollman AP. Zharkov DO, et al. Free Radic Biol Med. 2002 Jun 15;32(12):1254-63. doi: 10.1016/s0891-5849(02)00828-6. Free Radic Biol Med. 2002. PMID: 12057763 Review.

10

Structural characterization of the Fpg family of DNA glycosylases.

Zharkov DO, Shoham G, Grollman AP. Zharkov DO, et al. DNA Repair (Amst). 2003 Aug 12;2(8):839-62. doi: 10.1016/s1568-7864(03)00084-3. DNA Repair (Amst). 2003. PMID: 12893082 Review.

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