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Integrated, High-Throughput, Multiomics Platform Enables Data-Driven Construction of Cellular Responses and Reveals Global Drug Mechanisms of Action.
Norris JL, Farrow MA, Gutierrez DB, Palmer LD, Muszynski N, Sherrod SD, Pino JC, Allen JL, Spraggins JM, Lubbock AL, Jordan A, Burns W, Poland JC, Romer C, Manier ML, Nei YW, Prentice BM, Rose KL, Hill S, Van de Plas R, Tsui T, Braman NM, Keller MR, Rutherford SA, Lobdell N, Lopez CF, Lacy DB, McLean JA, Wikswo JP, Skaar EP, Caprioli RM. Norris JL, et al. Among authors: lopez cf. J Proteome Res. 2017 Mar 3;16(3):1364-1375. doi: 10.1021/acs.jproteome.6b01004. Epub 2017 Feb 9. J Proteome Res. 2017. PMID: 28088864
GPU-powered model analysis with PySB/cupSODA.
Harris LA, Nobile MS, Pino JC, Lubbock ALR, Besozzi D, Mauri G, Cazzaniga P, Lopez CF. Harris LA, et al. Among authors: lopez cf. Bioinformatics. 2017 Nov 1;33(21):3492-3494. doi: 10.1093/bioinformatics/btx420. Bioinformatics. 2017. PMID: 28666314 Free PMC article.
Processes in DNA damage response from a whole-cell multi-omics perspective.
Pino JC, Lubbock ALR, Harris LA, Gutierrez DB, Farrow MA, Muszynski N, Tsui T, Sherrod SD, Norris JL, McLean JA, Caprioli RM, Wikswo JP, Lopez CF. Pino JC, et al. Among authors: lopez cf. iScience. 2022 Oct 19;25(11):105341. doi: 10.1016/j.isci.2022.105341. eCollection 2022 Nov 18. iScience. 2022. PMID: 36339253 Free PMC article.
An unbiased metric of antiproliferative drug effect in vitro.
Harris LA, Frick PL, Garbett SP, Hardeman KN, Paudel BB, Lopez CF, Quaranta V, Tyson DR. Harris LA, et al. Among authors: lopez cf. Nat Methods. 2016 Jun;13(6):497-500. doi: 10.1038/nmeth.3852. Epub 2016 May 2. Nat Methods. 2016. PMID: 27135974 Free PMC article.
Selective Inhibition of JAK1 Primes STAT5-Driven Human Leukemia Cells for ATRA-Induced Differentiation.
Ramsey HE, Stengel K, Pino JC, Johnston G, Childress M, Gorska AE, Arrate PM, Fuller L, Villaume M, Fischer MA, Ferrell PB Jr, Roe CE, Zou J, Lubbock ALR, Stubbs M, Zinkel S, Irish JM, Lopez CF, Hiebert S, Savona MR. Ramsey HE, et al. Among authors: lopez cf. Target Oncol. 2021 Sep;16(5):663-674. doi: 10.1007/s11523-021-00830-5. Epub 2021 Jul 29. Target Oncol. 2021. PMID: 34324169 Free PMC article.
55 results