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Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment.
Schenk RL, Tuzlak S, Carrington EM, Zhan Y, Heinzel S, Teh CE, Gray DH, Tai L, Lew AM, Villunger A, Strasser A, Herold MJ. Schenk RL, et al. Among authors: tai l. Cell Death Differ. 2017 Mar;24(3):534-545. doi: 10.1038/cdd.2016.156. Epub 2017 Jan 13. Cell Death Differ. 2017. PMID: 28085150 Free PMC article.
Membrane-bound Fas ligand only is essential for Fas-induced apoptosis.
O' Reilly LA, Tai L, Lee L, Kruse EA, Grabow S, Fairlie WD, Haynes NM, Tarlinton DM, Zhang JG, Belz GT, Smyth MJ, Bouillet P, Robb L, Strasser A. O' Reilly LA, et al. Among authors: tai l. Nature. 2009 Oct 1;461(7264):659-63. doi: 10.1038/nature08402. Nature. 2009. PMID: 19794494 Free PMC article.
Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53.
Kelly GL, Grabow S, Glaser SP, Fitzsimmons L, Aubrey BJ, Okamoto T, Valente LJ, Robati M, Tai L, Fairlie WD, Lee EF, Lindstrom MS, Wiman KG, Huang DC, Bouillet P, Rowe M, Rickinson AB, Herold MJ, Strasser A. Kelly GL, et al. Among authors: tai l. Genes Dev. 2014 Jan 1;28(1):58-70. doi: 10.1101/gad.232009.113. Genes Dev. 2014. PMID: 24395247 Free PMC article.
Characterisation of a novel A1-specific monoclonal antibody.
Lang MJ, Brennan MS, O'Reilly LA, Ottina E, Czabotar PE, Whitlock E, Fairlie WD, Tai L, Strasser A, Herold MJ. Lang MJ, et al. Among authors: tai l. Cell Death Dis. 2014 Dec 4;5(12):e1553. doi: 10.1038/cddis.2014.519. Cell Death Dis. 2014. PMID: 25476901 Free PMC article. No abstract available.
521 results