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3,785 results

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Page 1
The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis.
Hao Z, Duncan GS, Su YW, Li WY, Silvester J, Hong C, You H, Brenner D, Gorrini C, Haight J, Wakeham A, You-Ten A, McCracken S, Elia A, Li Q, Detmar J, Jurisicova A, Hobeika E, Reth M, Sheng Y, Lang PA, Ohashi PS, Zhong Q, Wang X, Mak TW. Hao Z, et al. J Exp Med. 2012 Jan 16;209(1):173-86. doi: 10.1084/jem.20111363. Epub 2012 Jan 2. J Exp Med. 2012. PMID: 22213803 Free PMC article.
Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis.
Afzal S, Hao Z, Itsumi M, Abouelkheer Y, Brenner D, Gao Y, Wakeham A, Hong C, Li WY, Sylvester J, Gilani SO, Brüstle A, Haight J, You-Ten AJ, Lin GH, Inoue S, Mak TW. Afzal S, et al. Among authors: hao z. Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1119-24. doi: 10.1073/pnas.1423588112. Epub 2015 Jan 12. Proc Natl Acad Sci U S A. 2015. PMID: 25583492 Free PMC article.
14-3-3sigma regulates B-cell homeostasis through stabilization of FOXO1.
Su YW, Hao Z, Hirao A, Yamamoto K, Lin WJ, Young A, Duncan GS, Yoshida H, Wakeham A, Lang PA, Murakami K, Hermeking H, Vogelstein B, Ohashi P, Mak TW. Su YW, et al. Among authors: hao z. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1555-60. doi: 10.1073/pnas.1017729108. Epub 2011 Jan 4. Proc Natl Acad Sci U S A. 2011. PMID: 21205887 Free PMC article.
Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15.
Inoue S, Hao Z, Elia AJ, Cescon D, Zhou L, Silvester J, Snow B, Harris IS, Sasaki M, Li WY, Itsumi M, Yamamoto K, Ueda T, Dominguez-Brauer C, Gorrini C, Chio II, Haight J, You-Ten A, McCracken S, Wakeham A, Ghazarian D, Penn LJ, Melino G, Mak TW. Inoue S, et al. Among authors: hao z. Genes Dev. 2013 May 15;27(10):1101-14. doi: 10.1101/gad.214577.113. Genes Dev. 2013. PMID: 23699408 Free PMC article.
Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation.
Dominguez-Brauer C, Hao Z, Elia AJ, Fortin JM, Nechanitzky R, Brauer PM, Sheng Y, Mana MD, Chio IIC, Haight J, Pollett A, Cairns R, Tworzyanski L, Inoue S, Reardon C, Marques A, Silvester J, Cox MA, Wakeham A, Yilmaz OH, Sabatini DM, van Es JH, Clevers H, Sato T, Mak TW. Dominguez-Brauer C, et al. Among authors: hao z. Cell Stem Cell. 2016 Aug 4;19(2):205-216. doi: 10.1016/j.stem.2016.04.002. Epub 2016 May 12. Cell Stem Cell. 2016. PMID: 27184401 Free PMC article.
E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling.
Dominguez-Brauer C, Khatun R, Elia AJ, Thu KL, Ramachandran P, Baniasadi SP, Hao Z, Jones LD, Haight J, Sheng Y, Mak TW. Dominguez-Brauer C, et al. Among authors: hao z. Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):E1148-E1157. doi: 10.1073/pnas.1621355114. Epub 2017 Jan 30. Proc Natl Acad Sci U S A. 2017. PMID: 28137882 Free PMC article.
3,785 results