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Negative Regulation of Type 2 Immunity.
de Kouchkovsky DA, Ghosh S, Rothlin CV. de Kouchkovsky DA, et al. Among authors: rothlin cv. Trends Immunol. 2017 Mar;38(3):154-167. doi: 10.1016/j.it.2016.12.002. Epub 2017 Jan 9. Trends Immunol. 2017. PMID: 28082101 Free PMC article. Review.
T cell-derived protein S engages TAM receptor signaling in dendritic cells to control the magnitude of the immune response.
Carrera Silva EA, Chan PY, Joannas L, Errasti AE, Gagliani N, Bosurgi L, Jabbour M, Perry A, Smith-Chakmakova F, Mucida D, Cheroutre H, Burstyn-Cohen T, Leighton JA, Lemke G, Ghosh S, Rothlin CV. Carrera Silva EA, et al. Among authors: rothlin cv. Immunity. 2013 Jul 25;39(1):160-70. doi: 10.1016/j.immuni.2013.06.010. Epub 2013 Jul 11. Immunity. 2013. PMID: 23850380 Free PMC article.
Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.
Kusne Y, Carrera-Silva EA, Perry AS, Rushing EJ, Mandell EK, Dietrich JD, Errasti AE, Gibbs D, Berens ME, Loftus JC, Hulme C, Yang W, Lu Z, Aldape K, Sanai N, Rothlin CV, Ghosh S. Kusne Y, et al. Among authors: rothlin cv. Sci Signal. 2014 Aug 12;7(338):ra75. doi: 10.1126/scisignal.2005196. Sci Signal. 2014. PMID: 25118327 Free PMC article.
TAM receptor signaling in immune homeostasis.
Rothlin CV, Carrera-Silva EA, Bosurgi L, Ghosh S. Rothlin CV, et al. Annu Rev Immunol. 2015;33:355-91. doi: 10.1146/annurev-immunol-032414-112103. Epub 2015 Jan 14. Annu Rev Immunol. 2015. PMID: 25594431 Free PMC article. Review.
The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity.
Chan PY, Carrera Silva EA, De Kouchkovsky D, Joannas LD, Hao L, Hu D, Huntsman S, Eng C, Licona-Limón P, Weinstein JS, Herbert DR, Craft JE, Flavell RA, Repetto S, Correale J, Burchard EG, Torgerson DG, Ghosh S, Rothlin CV. Chan PY, et al. Among authors: rothlin cv. Science. 2016 Apr 1;352(6281):99-103. doi: 10.1126/science.aaf1358. Science. 2016. PMID: 27034374 Free PMC article.
Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells.
Bosurgi L, Cao YG, Cabeza-Cabrerizo M, Tucci A, Hughes LD, Kong Y, Weinstein JS, Licona-Limon P, Schmid ET, Pelorosso F, Gagliani N, Craft JE, Flavell RA, Ghosh S, Rothlin CV. Bosurgi L, et al. Among authors: rothlin cv. Science. 2017 Jun 9;356(6342):1072-1076. doi: 10.1126/science.aai8132. Epub 2017 May 11. Science. 2017. PMID: 28495875 Free PMC article.
91 results