Arnaout MA - Search Results

1

Prophylactic orthosteric inhibition of leukocyte integrin CD11b/CD18 prevents long-term fibrotic kidney failure in cynomolgus monkeys.

Dehnadi A, Benedict Cosimi A, Neal Smith R, Li X, Alonso JL, Means TK, Arnaout MA. Dehnadi A, et al. Among authors: arnaout ma. Nat Commun. 2017 Jan 10;8:13899. doi: 10.1038/ncomms13899. Nat Commun. 2017. PMID: 28071653 Free PMC article.

2

The transcription factor ZBP-89 controls generation of the hematopoietic lineage in zebrafish and mouse embryonic stem cells.

Li X, Xiong JW, Shelley CS, Park H, Arnaout MA. Li X, et al. Among authors: arnaout ma. Development. 2006 Sep;133(18):3641-50. doi: 10.1242/dev.02540. Epub 2006 Aug 16. Development. 2006. PMID: 16914492

3

The beta-tail domain (betaTD) regulates physiologic ligand binding to integrin CD11b/CD18.

Gupta V, Gylling A, Alonso JL, Sugimori T, Ianakiev P, Xiong JP, Arnaout MA. Gupta V, et al. Among authors: arnaout ma. Blood. 2007 Apr 15;109(8):3513-20. doi: 10.1182/blood-2005-11-056689. Epub 2006 Dec 14. Blood. 2007. PMID: 17170130 Free PMC article.

4

A simple, no-wash cell adhesion-based high-throughput assay for the discovery of small-molecule regulators of the integrin CD11b/CD18.

Park JY, Arnaout MA, Gupta V. Park JY, et al. Among authors: arnaout ma. J Biomol Screen. 2007 Apr;12(3):406-17. doi: 10.1177/1087057106299162. J Biomol Screen. 2007. PMID: 17438069 Free PMC article.

5

Role of the beta-subunit arginine/lysine finger in integrin heterodimer formation and function.

Gupta V, Alonso JL, Sugimori T, Essafi M, Xiong JP, Arnaout MA. Gupta V, et al. Among authors: arnaout ma. J Immunol. 2008 Feb 1;180(3):1713-8. doi: 10.4049/jimmunol.180.3.1713. J Immunol. 2008. PMID: 18209068 Free PMC article.

6

Crystal structure of the complete integrin alphaVbeta3 ectodomain plus an alpha/beta transmembrane fragment.

Xiong JP, Mahalingham B, Alonso JL, Borrelli LA, Rui X, Anand S, Hyman BT, Rysiok T, Müller-Pompalla D, Goodman SL, Arnaout MA. Xiong JP, et al. Among authors: arnaout ma. J Cell Biol. 2009 Aug 24;186(4):589-600. doi: 10.1083/jcb.200905085. J Cell Biol. 2009. PMID: 19704023 Free PMC article.

7

Stable coordination of the inhibitory Ca2+ ion at the metal ion-dependent adhesion site in integrin CD11b/CD18 by an antibody-derived ligand aspartate: implications for integrin regulation and structure-based drug design.

Mahalingam B, Ajroud K, Alonso JL, Anand S, Adair BD, Horenstein AL, Malavasi F, Xiong JP, Arnaout MA. Mahalingam B, et al. Among authors: arnaout ma. J Immunol. 2011 Dec 15;187(12):6393-401. doi: 10.4049/jimmunol.1102394. Epub 2011 Nov 16. J Immunol. 2011. PMID: 22095715 Free PMC article.

8

EM structure of the ectodomain of integrin CD11b/CD18 and localization of its ligand-binding site relative to the plasma membrane.

Adair BD, Xiong JP, Alonso JL, Hyman BT, Arnaout MA. Adair BD, et al. Among authors: arnaout ma. PLoS One. 2013;8(2):e57951. doi: 10.1371/journal.pone.0057951. Epub 2013 Feb 28. PLoS One. 2013. PMID: 23469114 Free PMC article.

9

Topographically-patterned porous membranes in a microfluidic device as an in vitro model of renal reabsorptive barriers.

Frohlich EM, Alonso JL, Borenstein JT, Zhang X, Arnaout MA, Charest JL. Frohlich EM, et al. Among authors: arnaout ma. Lab Chip. 2013 Jun 21;13(12):2311-9. doi: 10.1039/c3lc50199j. Epub 2013 May 2. Lab Chip. 2013. PMID: 23636129 Free PMC article.

10

Stress hematopoiesis is regulated by the Krüppel-like transcription factor ZBP-89.

Li X, Romain RD, Park D, Scadden DT, Merchant JL, Arnaout MA. Li X, et al. Among authors: arnaout ma. Stem Cells. 2014 Mar;32(3):791-801. doi: 10.1002/stem.1598. Stem Cells. 2014. PMID: 24549639 Free PMC article.

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