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LRRK2 and GBA1 variant carriers have higher urinary bis(monacylglycerol) phosphate concentrations in PPMI cohorts.
Merchant KM, Simuni T, Fedler J, Caspell-Garcia C, Brumm M, Nudelman KNH, Tengstrandt E, Hsieh F, Alcalay RN, Coffey C, Chahine L, Foroud T, Singleton A, Weintraub D, Hutten S, Sherer T, Mollenhauer B, Siderowf A, Tanner C, Marek K; the Parkinson’s Progression Markers Initiative. Merchant KM, et al. NPJ Parkinsons Dis. 2023 Feb 28;9(1):30. doi: 10.1038/s41531-023-00468-2. NPJ Parkinsons Dis. 2023. PMID: 36854767 Free PMC article.
Specifically neuropathic Gaucher's mutations accelerate cognitive decline in Parkinson's.
Liu G, Boot B, Locascio JJ, Jansen IE, Winder-Rhodes S, Eberly S, Elbaz A, Brice A, Ravina B, van Hilten JJ, Cormier-Dequaire F, Corvol JC, Barker RA, Heutink P, Marinus J, Williams-Gray CH, Scherzer CR; International Genetics of Parkinson Disease Progression (IGPP) Consortium. Liu G, et al. Ann Neurol. 2016 Nov;80(5):674-685. doi: 10.1002/ana.24781. Ann Neurol. 2016. PMID: 27717005 Free PMC article.
A user's guide for α-synuclein biomarker studies in biological fluids: Perianalytical considerations.
Mollenhauer B, Batrla R, El-Agnaf O, Galasko DR, Lashuel HA, Merchant KM, Shaw LM, Selkoe DJ, Umek R, Vanderstichele H, Zetterberg H, Zhang J, Caspell-Garcia C, Coffey C, Hutten SJ, Frasier M, Taylor P; Investigating Synuclein Consortium of the Michael J. Fox Foundation for Parkinson's Research. Mollenhauer B, et al. Among authors: hutten sj. Mov Disord. 2017 Aug;32(8):1117-1130. doi: 10.1002/mds.27090. Epub 2017 Jul 22. Mov Disord. 2017. PMID: 28734051 Free PMC article. Review.
A Proposed Roadmap for Parkinson's Disease Proof of Concept Clinical Trials Investigating Compounds Targeting Alpha-Synuclein.
Merchant KM, Cedarbaum JM, Brundin P, Dave KD, Eberling J, Espay AJ, Hutten SJ, Javidnia M, Luthman J, Maetzler W, Menalled L, Reimer AN, Stoessl AJ, Weiner DM; The Michael J. Fox Foundation Alpha Synuclein Clinical Path Working Group. Merchant KM, et al. Among authors: hutten sj. J Parkinsons Dis. 2019;9(1):31-61. doi: 10.3233/JPD-181471. J Parkinsons Dis. 2019. PMID: 30400107 Free PMC article.
Longitudinal Analysis of Multiple Neurotransmitter Metabolites in Cerebrospinal Fluid in Early Parkinson's Disease.
Kremer T, Taylor KI, Siebourg-Polster J, Gerken T, Staempfli A, Czech C, Dukart J, Galasko D, Foroud T, Chahine LM, Coffey CS, Simuni T, Weintraub D, Seibyl J, Poston KL, Toga AW, Tanner CM, Marek K, Hutten SJ, Dziadek S, Trenkwalder C, Pagano G, Mollenhauer B. Kremer T, et al. Among authors: hutten sj. Mov Disord. 2021 Aug;36(8):1972-1978. doi: 10.1002/mds.28608. Epub 2021 May 4. Mov Disord. 2021. PMID: 33942926 Free PMC article.
High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease.
Russo MJ, Orru CD, Concha-Marambio L, Giaisi S, Groveman BR, Farris CM, Holguin B, Hughson AG, LaFontant DE, Caspell-Garcia C, Coffey CS, Mollon J, Hutten SJ, Merchant K, Heym RG, Soto C, Caughey B, Kang UJ. Russo MJ, et al. Among authors: hutten sj. Acta Neuropathol Commun. 2021 Nov 6;9(1):179. doi: 10.1186/s40478-021-01282-8. Acta Neuropathol Commun. 2021. PMID: 34742348 Free PMC article.
41 results