Thorp EB - Search Results

1

MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis.

Cai B, Thorp EB, Doran AC, Sansbury BE, Daemen MJ, Dorweiler B, Spite M, Fredman G, Tabas I. Cai B, et al. Among authors: thorp eb. J Clin Invest. 2017 Feb 1;127(2):564-568. doi: 10.1172/JCI90520. Epub 2017 Jan 9. J Clin Invest. 2017. PMID: 28067670 Free PMC article.

2

MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation.

Cai B, Thorp EB, Doran AC, Subramanian M, Sansbury BE, Lin CS, Spite M, Fredman G, Tabas I. Cai B, et al. Among authors: thorp eb. Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):6526-31. doi: 10.1073/pnas.1524292113. Epub 2016 May 19. Proc Natl Acad Sci U S A. 2016. PMID: 27199481 Free PMC article.

3

Macrophage AXL receptor tyrosine kinase inflames the heart after reperfused myocardial infarction.

DeBerge M, Glinton K, Subramanian M, Wilsbacher LD, Rothlin CV, Tabas I, Thorp EB. DeBerge M, et al. Among authors: thorp eb. J Clin Invest. 2021 Mar 15;131(6):e139576. doi: 10.1172/JCI139576. J Clin Invest. 2021. PMID: 33529176 Free PMC article.

4

Mertk receptor mutation reduces efferocytosis efficiency and promotes apoptotic cell accumulation and plaque necrosis in atherosclerotic lesions of apoe-/- mice.

Thorp E, Cui D, Schrijvers DM, Kuriakose G, Tabas I. Thorp E, et al. Arterioscler Thromb Vasc Biol. 2008 Aug;28(8):1421-8. doi: 10.1161/ATVBAHA.108.167197. Epub 2008 May 1. Arterioscler Thromb Vasc Biol. 2008. PMID: 18451332 Free PMC article.

5

Treg-mediated suppression of atherosclerosis requires MYD88 signaling in DCs.

Subramanian M, Thorp E, Hansson GK, Tabas I. Subramanian M, et al. J Clin Invest. 2013 Jan;123(1):179-88. doi: 10.1172/JCI64617. Epub 2012 Dec 21. J Clin Invest. 2013. PMID: 23257360 Free PMC article.

6

An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo.

Subramanian M, Hayes CD, Thome JJ, Thorp E, Matsushima GK, Herz J, Farber DL, Liu K, Lakshmana M, Tabas I. Subramanian M, et al. J Clin Invest. 2014 Mar;124(3):1296-308. doi: 10.1172/JCI72051. Epub 2014 Feb 10. J Clin Invest. 2014. PMID: 24509082 Free PMC article.

7

Identification of a non-growth factor role for GM-CSF in advanced atherosclerosis: promotion of macrophage apoptosis and plaque necrosis through IL-23 signaling.

Subramanian M, Thorp E, Tabas I. Subramanian M, et al. Circ Res. 2015 Jan 16;116(2):e13-24. doi: 10.1161/CIRCRESAHA.116.304794. Epub 2014 Oct 27. Circ Res. 2015. PMID: 25348165 Free PMC article.

8

MerTK Cleavage on Resident Cardiac Macrophages Compromises Repair After Myocardial Ischemia Reperfusion Injury.

DeBerge M, Yeap XY, Dehn S, Zhang S, Grigoryeva L, Misener S, Procissi D, Zhou X, Lee DC, Muller WA, Luo X, Rothlin C, Tabas I, Thorp EB. DeBerge M, et al. Among authors: thorp eb. Circ Res. 2017 Sep 29;121(8):930-940. doi: 10.1161/CIRCRESAHA.117.311327. Epub 2017 Aug 29. Circ Res. 2017. PMID: 28851810 Free PMC article.

9

Mechanisms and consequences of efferocytosis in advanced atherosclerosis.

Thorp E, Tabas I. Thorp E, et al. J Leukoc Biol. 2009 Nov;86(5):1089-95. doi: 10.1189/jlb.0209115. Epub 2009 May 4. J Leukoc Biol. 2009. PMID: 19414539 Free PMC article. Review.

10

Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP.

Thorp E, Li G, Seimon TA, Kuriakose G, Ron D, Tabas I. Thorp E, et al. Cell Metab. 2009 May;9(5):474-81. doi: 10.1016/j.cmet.2009.03.003. Cell Metab. 2009. PMID: 19416717 Free PMC article.

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