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Insights into the Mechanistic Basis of Plasmid-Mediated Colistin Resistance from Crystal Structures of the Catalytic Domain of MCR-1.
Hinchliffe P, Yang QE, Portal E, Young T, Li H, Tooke CL, Carvalho MJ, Paterson NG, Brem J, Niumsup PR, Tansawai U, Lei L, Li M, Shen Z, Wang Y, Schofield CJ, Mulholland AJ, Shen J, Fey N, Walsh TR, Spencer J. Hinchliffe P, et al. Among authors: walsh tr. Sci Rep. 2017 Jan 6;7:39392. doi: 10.1038/srep39392. Sci Rep. 2017. PMID: 28059088 Free PMC article.
A new approach to the inhibition of metallo-beta-lactamases.
Spencer J, Walsh TR. Spencer J, et al. Among authors: walsh tr. Angew Chem Int Ed Engl. 2006 Feb 6;45(7):1022-6. doi: 10.1002/anie.200502984. Angew Chem Int Ed Engl. 2006. PMID: 16404761 Review. No abstract available.
Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers.
Brem J, van Berkel SS, Zollman D, Lee SY, Gileadi O, McHugh PJ, Walsh TR, McDonough MA, Schofield CJ. Brem J, et al. Among authors: walsh tr. Antimicrob Agents Chemother. 2015 Oct 19;60(1):142-50. doi: 10.1128/AAC.01335-15. Print 2016 Jan. Antimicrob Agents Chemother. 2015. PMID: 26482303 Free PMC article.
Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study.
Liu YY, Wang Y, Walsh TR, Yi LX, Zhang R, Spencer J, Doi Y, Tian G, Dong B, Huang X, Yu LF, Gu D, Ren H, Chen X, Lv L, He D, Zhou H, Liang Z, Liu JH, Shen J. Liu YY, et al. Among authors: walsh tr. Lancet Infect Dis. 2016 Feb;16(2):161-8. doi: 10.1016/S1473-3099(15)00424-7. Epub 2015 Nov 19. Lancet Infect Dis. 2016. PMID: 26603172
422 results