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Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Mills-Davies N, Butler D, Norton E, Thompson D, Sarwar M, Guo J, Gill R, Azim N, Coker A, Wood SP, Erskine PT, Coates L, Cooper JB, Rashid N, Akhtar M, Shoolingin-Jordan PM. Mills-Davies N, et al. Among authors: thompson d. Acta Crystallogr D Struct Biol. 2017 Jan 1;73(Pt 1):9-21. doi: 10.1107/S2059798316019525. Epub 2017 Jan 1. Acta Crystallogr D Struct Biol. 2017. PMID: 28045381
Interaction of serum amyloid P component with hexanoyl bis(D-proline) (CPHPC).
Kolstoe SE, Jenvey MC, Purvis A, Light ME, Thompson D, Hughes P, Pepys MB, Wood SP. Kolstoe SE, et al. Among authors: thompson d. Acta Crystallogr D Biol Crystallogr. 2014 Aug;70(Pt 8):2232-40. doi: 10.1107/S1399004714013455. Epub 2014 Jul 25. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 25084341 Free PMC article.
Overproduction, purification and preliminary X-ray diffraction analysis of YncE, an iron-regulated Sec-dependent periplasmic protein from Escherichia coli.
Baba-Dikwa A, Thompson D, Spencer NJ, Andrews SC, Watson KA. Baba-Dikwa A, et al. Among authors: thompson d. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Oct 1;64(Pt 10):966-9. doi: 10.1107/S1744309108029515. Epub 2008 Sep 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 18931447 Free PMC article.
Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis.
Pepys MB, Herbert J, Hutchinson WL, Tennent GA, Lachmann HJ, Gallimore JR, Lovat LB, Bartfai T, Alanine A, Hertel C, Hoffmann T, Jakob-Roetne R, Norcross RD, Kemp JA, Yamamura K, Suzuki M, Taylor GW, Murray S, Thompson D, Purvis A, Kolstoe S, Wood SP, Hawkins PN. Pepys MB, et al. Among authors: thompson d. Nature. 2002 May 16;417(6886):254-9. doi: 10.1038/417254a. Nature. 2002. PMID: 12015594
Targeting C-reactive protein for the treatment of cardiovascular disease.
Pepys MB, Hirschfield GM, Tennent GA, Gallimore JR, Kahan MC, Bellotti V, Hawkins PN, Myers RM, Smith MD, Polara A, Cobb AJ, Ley SV, Aquilina JA, Robinson CV, Sharif I, Gray GA, Sabin CA, Jenvey MC, Kolstoe SE, Thompson D, Wood SP. Pepys MB, et al. Among authors: thompson d. Nature. 2006 Apr 27;440(7088):1217-21. doi: 10.1038/nature04672. Nature. 2006. PMID: 16642000
6,899 results