Carie A - Search Results

1

Stabilized Polymer Micelles for the Development of IT-147, an Epothilone D Drug-Loaded Formulation.

Carie A, Sullivan B, Ellis T, Semple JE, Buley T, Costich TL, Crouse R, Bakewell S, Sill K. Carie A, et al. J Drug Deliv. 2016;2016:8046739. doi: 10.1155/2016/8046739. Epub 2016 Dec 1. J Drug Deliv. 2016. PMID: 28044108 Free PMC article.

2

IT-141, a Polymer Micelle Encapsulating SN-38, Induces Tumor Regression in Multiple Colorectal Cancer Models.

Carie A, Rios-Doria J, Costich T, Burke B, Slama R, Skaff H, Sill K. Carie A, et al. J Drug Deliv. 2011;2011:869027. doi: 10.1155/2011/869027. Epub 2011 Dec 6. J Drug Deliv. 2011. PMID: 22187652 Free PMC article.

3

A versatile polymer micelle drug delivery system for encapsulation and in vivo stabilization of hydrophobic anticancer drugs.

Rios-Doria J, Carie A, Costich T, Burke B, Skaff H, Panicucci R, Sill K. Rios-Doria J, et al. Among authors: carie a. J Drug Deliv. 2012;2012:951741. doi: 10.1155/2012/951741. Epub 2012 Feb 1. J Drug Deliv. 2012. PMID: 22518317 Free PMC article.

4

Imaging the delivery of drug-loaded, iron-stabilized micelles.

Bakewell SJ, Carie A, Costich TL, Sethuraman J, Semple JE, Sullivan B, Martinez GV, Dominguez-Viqueira W, Sill KN. Bakewell SJ, et al. Among authors: carie a. Nanomedicine. 2017 May;13(4):1353-1362. doi: 10.1016/j.nano.2017.01.009. Epub 2017 Jan 20. Nanomedicine. 2017. PMID: 28115246 Free PMC article.

5

Synthesis and Characterization of Micelle-Forming PEG-Poly(Amino Acid) Copolymers with Iron-Hydroxamate Cross-Linkable Blocks for Encapsulation and Release of Hydrophobic Drugs.

Sill KN, Sullivan B, Carie A, Semple JE. Sill KN, et al. Among authors: carie a. Biomacromolecules. 2017 Jun 12;18(6):1874-1884. doi: 10.1021/acs.biomac.7b00317. Epub 2017 May 11. Biomacromolecules. 2017. PMID: 28475303 Free article.

6

Development and in vivo quantitative magnetic resonance imaging of polymer micelles targeted to the melanocortin 1 receptor.

Barkey NM, Preihs C, Cornnell HH, Martinez G, Carie A, Vagner J, Xu L, Lloyd MC, Lynch VM, Hruby VJ, Sessler JL, Sill KN, Gillies RJ, Morse DL. Barkey NM, et al. Among authors: carie a. J Med Chem. 2013 Aug 22;56(16):6330-8. doi: 10.1021/jm4005576. Epub 2013 Aug 9. J Med Chem. 2013. PMID: 23863078 Free PMC article.

7

A chemical biology approach identifies a beta-2 adrenergic receptor agonist that causes human tumor regression by blocking the Raf-1/Mek-1/Erk1/2 pathway.

Carie AE, Sebti SM. Carie AE, et al. Oncogene. 2007 May 31;26(26):3777-88. doi: 10.1038/sj.onc.1210172. Epub 2007 Jan 29. Oncogene. 2007. PMID: 17260025

8

Blockade of protein geranylgeranylation inhibits Cdk2-dependent p27Kip1 phosphorylation on Thr187 and accumulates p27Kip1 in the nucleus: implications for breast cancer therapy.

Kazi A, Carie A, Blaskovich MA, Bucher C, Thai V, Moulder S, Peng H, Carrico D, Pusateri E, Pledger WJ, Berndt N, Hamilton A, Sebti SM. Kazi A, et al. Among authors: carie a. Mol Cell Biol. 2009 Apr;29(8):2254-63. doi: 10.1128/MCB.01029-08. Epub 2009 Feb 9. Mol Cell Biol. 2009. PMID: 19204084 Free PMC article.

9

A small molecule disruptor of Rb/Raf-1 interaction inhibits cell proliferation, angiogenesis, and growth of human tumor xenografts in nude mice.

Kinkade R, Dasgupta P, Carie A, Pernazza D, Carless M, Pillai S, Lawrence N, Sebti SM, Chellappan S. Kinkade R, et al. Among authors: carie a. Cancer Res. 2008 May 15;68(10):3810-8. doi: 10.1158/0008-5472.CAN-07-6672. Cancer Res. 2008. PMID: 18483265 Free PMC article.

10

Inhibiting angiogenesis and tumorigenesis by a synthetic molecule that blocks binding of both VEGF and PDGF to their receptors.

Sun J, Wang DA, Jain RK, Carie A, Paquette S, Ennis E, Blaskovich MA, Baldini L, Coppola D, Hamilton AD, Sebti SM. Sun J, et al. Among authors: carie a. Oncogene. 2005 Jul 7;24(29):4701-9. doi: 10.1038/sj.onc.1208391. Oncogene. 2005. PMID: 15897913

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