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Pharmacokinetics of a Single Oral Dose of the MEK1/2 Inhibitor Selumetinib in Subjects With End-Stage Renal Disease or Varying Degrees of Hepatic Impairment Compared With Healthy Subjects.
Dymond AW, Martin P, So K, Huang Y, Severin P, Holmes V, Mariani G, Marbury T. Dymond AW, et al. Among authors: huang y. J Clin Pharmacol. 2017 May;57(5):592-605. doi: 10.1002/jcph.848. Epub 2016 Dec 26. J Clin Pharmacol. 2017. PMID: 28019010 Free PMC article. Clinical Trial.
Evaluation of the Effect of Selumetinib on Cardiac Repolarization: A Randomized, Placebo- and Positive-controlled Crossover QT/QTc Study in Healthy Subjects.
Zhou D, So K, Dymond AW, Vik T, Al-Huniti N, Mariani G, Zorenyi G, Huang Y, Holmes V, Severin P, Rasmussen S, Martin P. Zhou D, et al. Among authors: huang y. Clin Ther. 2016 Dec;38(12):2555-2566. doi: 10.1016/j.clinthera.2016.10.004. Epub 2016 Nov 9. Clin Ther. 2016. PMID: 27837934 Free article. Clinical Trial.
Effects of cytochrome P450 (CYP3A4 and CYP2C19) inhibition and induction on the exposure of selumetinib, a MEK1/2 inhibitor, in healthy subjects: results from two clinical trials.
Dymond AW, So K, Martin P, Huang Y, Severin P, Mathews D, Lisbon E, Mariani G. Dymond AW, et al. Among authors: huang y. Eur J Clin Pharmacol. 2017 Feb;73(2):175-184. doi: 10.1007/s00228-016-2153-7. Epub 2016 Nov 26. Eur J Clin Pharmacol. 2017. PMID: 27889832 Free PMC article. Clinical Trial.
Association of dietary and plasma fatty acids with periodontitis: Results from the 2009-2014 National Health and Nutrition Examination Survey and Mendelian randomization study.
Xie B, Wu Y, Liu Z, Huang Y, Lu Q, Bian A, Han B, Yan Y, Lai Y, He B, Li Y, Yan F, Yan L, Chen F. Xie B, et al. Among authors: huang y. J Am Dent Assoc. 2025 Jan 24:S0002-8177(24)00696-2. doi: 10.1016/j.adaj.2024.11.010. Online ahead of print. J Am Dent Assoc. 2025. PMID: 39864010
Evolutionary dynamics of SARS-CoV-2 variants under strict non-pharmaceutical interventions - a population-based study.
Huo X, Cui L, Zhu L, Zhang J, Fan H, Yi Y, Zhao J, Ge Y, Wang S, Han X, Gao X, Qi X, Fu J, Li Z, Fan H, Yu H, Deng F, Zhao K, Zhu X, Hu J, Li J, Ai J, Kang G, Shen Y, Jin G, Wang F, Zhang Z, He M, Ding S, Wang Y, Dong Y, Huang Y, Yi C, Wang L, Jiao Y, Wang J, Li J, Liu H, Li J, Bao C, Wu M, Zhu F. Huo X, et al. Among authors: huang y. J Infect Dev Ctries. 2024 Dec 31;18(12.1):S214-S226. doi: 10.3855/jidc.19409. J Infect Dev Ctries. 2024. PMID: 39863937
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