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Selection and early clinical evaluation of the brain-penetrant 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor UE2343 (Xanamem™).
Webster SP, McBride A, Binnie M, Sooy K, Seckl JR, Andrew R, Pallin TD, Hunt HJ, Perrior TR, Ruffles VS, Ketelbey JW, Boyd A, Walker BR. Webster SP, et al. Among authors: andrew r. Br J Pharmacol. 2017 Mar;174(5):396-408. doi: 10.1111/bph.13699. Epub 2017 Jan 25. Br J Pharmacol. 2017. PMID: 28012176 Free PMC article. Clinical Trial.
Increased glucocorticoid activity in men with cardiovascular risk factors.
Walker BR, Phillips DI, Noon JP, Panarelli M, Andrew R, Edwards HV, Holton DW, Seckl JR, Webb DJ, Watt GC. Walker BR, et al. Among authors: andrew r. Hypertension. 1998 Apr;31(4):891-5. doi: 10.1161/01.hyp.31.4.891. Hypertension. 1998. PMID: 9535410 Clinical Trial.
553 results