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261 results

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Page 1
Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen.
Cheeseman MD, Chessum NE, Rye CS, Pasqua AE, Tucker MJ, Wilding B, Evans LE, Lepri S, Richards M, Sharp SY, Ali S, Rowlands M, O'Fee L, Miah A, Hayes A, Henley AT, Powers M, Te Poele R, De Billy E, Pellegrino L, Raynaud F, Burke R, van Montfort RL, Eccles SA, Workman P, Jones K. Cheeseman MD, et al. Among authors: pellegrino l. J Med Chem. 2017 Jan 12;60(1):180-201. doi: 10.1021/acs.jmedchem.6b01055. Epub 2016 Dec 22. J Med Chem. 2017. PMID: 28004573 Free PMC article.
Growth arrest-specific transcript 5 associated snoRNA levels are related to p53 expression and DNA damage in colorectal cancer.
Krell J, Frampton AE, Mirnezami R, Harding V, De Giorgio A, Roca Alonso L, Cohen P, Ottaviani S, Colombo T, Jacob J, Pellegrino L, Buchanan G, Stebbing J, Castellano L. Krell J, et al. Among authors: pellegrino l. PLoS One. 2014 Jun 13;9(6):e98561. doi: 10.1371/journal.pone.0098561. eCollection 2014. PLoS One. 2014. PMID: 24926850 Free PMC article.
Downregulation of microRNA-515-5p by the estrogen receptor modulates sphingosine kinase 1 and breast cancer cell proliferation.
Pinho FG, Frampton AE, Nunes J, Krell J, Alshaker H, Jacob J, Pellegrino L, Roca-Alonso L, de Giorgio A, Harding V, Waxman J, Stebbing J, Pchejetski D, Castellano L. Pinho FG, et al. Among authors: pellegrino l. Cancer Res. 2013 Oct 1;73(19):5936-48. doi: 10.1158/0008-5472.CAN-13-0158. Epub 2013 Aug 8. Cancer Res. 2013. PMID: 23928990
miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts.
Pellegrino L, Stebbing J, Braga VM, Frampton AE, Jacob J, Buluwela L, Jiao LR, Periyasamy M, Madsen CD, Caley MP, Ottaviani S, Roca-Alonso L, El-Bahrawy M, Coombes RC, Krell J, Castellano L. Pellegrino L, et al. Nucleic Acids Res. 2013 May 1;41(10):5400-12. doi: 10.1093/nar/gkt245. Epub 2013 Apr 10. Nucleic Acids Res. 2013. PMID: 23580553 Free PMC article.
MicroRNAs cooperatively inhibit a network of tumor suppressor genes to promote pancreatic tumor growth and progression.
Frampton AE, Castellano L, Colombo T, Giovannetti E, Krell J, Jacob J, Pellegrino L, Roca-Alonso L, Funel N, Gall TM, De Giorgio A, Pinho FG, Fulci V, Britton DJ, Ahmad R, Habib NA, Coombes RC, Harding V, Knösel T, Stebbing J, Jiao LR. Frampton AE, et al. Among authors: pellegrino l. Gastroenterology. 2014 Jan;146(1):268-77.e18. doi: 10.1053/j.gastro.2013.10.010. Epub 2013 Oct 9. Gastroenterology. 2014. PMID: 24120476
261 results