Chatrikhi R - Search Results

1

SF1 Phosphorylation Enhances Specific Binding to U2AF⁶⁵ and Reduces Binding to 3'-Splice-Site RNA.

Chatrikhi R, Wang W, Gupta A, Loerch S, Maucuer A, Kielkopf CL. Chatrikhi R, et al. Biophys J. 2016 Dec 20;111(12):2570-2586. doi: 10.1016/j.bpj.2016.11.007. Biophys J. 2016. PMID: 28002734 Free PMC article.

2

An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal.

Agrawal AA, Salsi E, Chatrikhi R, Henderson S, Jenkins JL, Green MR, Ermolenko DN, Kielkopf CL. Agrawal AA, et al. Among authors: chatrikhi r. Nat Commun. 2016 Mar 8;7:10950. doi: 10.1038/ncomms10950. Nat Commun. 2016. PMID: 26952537 Free PMC article.

3

Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival.

Fei DL, Motowski H, Chatrikhi R, Prasad S, Yu J, Gao S, Kielkopf CL, Bradley RK, Varmus H. Fei DL, et al. Among authors: chatrikhi r. PLoS Genet. 2016 Oct 24;12(10):e1006384. doi: 10.1371/journal.pgen.1006384. eCollection 2016 Oct. PLoS Genet. 2016. PMID: 27776121 Free PMC article.

4

A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex.

Chatrikhi R, Feeney CF, Pulvino MJ, Alachouzos G, MacRae AJ, Falls Z, Rai S, Brennessel WW, Jenkins JL, Walter MJ, Graubert TA, Samudrala R, Jurica MS, Frontier AJ, Kielkopf CL. Chatrikhi R, et al. Cell Chem Biol. 2021 Aug 19;28(8):1145-1157.e6. doi: 10.1016/j.chembiol.2021.02.007. Epub 2021 Mar 8. Cell Chem Biol. 2021. PMID: 33689684 Free PMC article.

5

U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing.

Okeyo-Owuor T, White BS, Chatrikhi R, Mohan DR, Kim S, Griffith M, Ding L, Ketkar-Kulkarni S, Hundal J, Laird KM, Kielkopf CL, Ley TJ, Walter MJ, Graubert TA. Okeyo-Owuor T, et al. Among authors: chatrikhi r. Leukemia. 2015 Apr;29(4):909-17. doi: 10.1038/leu.2014.303. Epub 2014 Oct 14. Leukemia. 2015. PMID: 25311244 Free PMC article.

6

Reciprocal regulation of hnRNP C and CELF2 through translation and transcription tunes splicing activity in T cells.

Mallory MJ, McClory SP, Chatrikhi R, Gazzara MR, Ontiveros RJ, Lynch KW. Mallory MJ, et al. Among authors: chatrikhi r. Nucleic Acids Res. 2020 Jun 4;48(10):5710-5719. doi: 10.1093/nar/gkaa295. Nucleic Acids Res. 2020. PMID: 32338744 Free PMC article.

7

RNA Binding Protein CELF2 Regulates Signal-Induced Alternative Polyadenylation by Competing with Enhancers of the Polyadenylation Machinery.

Chatrikhi R, Mallory MJ, Gazzara MR, Agosto LM, Zhu WS, Litterman AJ, Ansel KM, Lynch KW. Chatrikhi R, et al. Cell Rep. 2019 Sep 10;28(11):2795-2806.e3. doi: 10.1016/j.celrep.2019.08.022. Cell Rep. 2019. PMID: 31509743 Free PMC article.

8

Alternative splicing redefines landscape of commonly mutated genes in acute myeloid leukemia.

Rivera OD, Mallory MJ, Quesnel-Vallières M, Chatrikhi R, Schultz DC, Carroll M, Barash Y, Cherry S, Lynch KW. Rivera OD, et al. Among authors: chatrikhi r. Proc Natl Acad Sci U S A. 2021 Apr 13;118(15):e2014967118. doi: 10.1073/pnas.2014967118. Proc Natl Acad Sci U S A. 2021. PMID: 33876749 Free PMC article.

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