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Inhibitors of Mycobacterium tuberculosis DosRST signaling and persistence.
Zheng H, Colvin CJ, Johnson BK, Kirchhoff PD, Wilson M, Jorgensen-Muga K, Larsen SD, Abramovitch RB. Zheng H, et al. Among authors: abramovitch rb. Nat Chem Biol. 2017 Feb;13(2):218-225. doi: 10.1038/nchembio.2259. Epub 2016 Dec 19. Nat Chem Biol. 2017. PMID: 27992879
Small Molecules That Sabotage Bacterial Virulence.
Johnson BK, Abramovitch RB. Johnson BK, et al. Among authors: abramovitch rb. Trends Pharmacol Sci. 2017 Apr;38(4):339-362. doi: 10.1016/j.tips.2017.01.004. Epub 2017 Feb 14. Trends Pharmacol Sci. 2017. PMID: 28209403 Free PMC article. Review.
2-aminoimidazoles potentiate ß-lactam antimicrobial activity against Mycobacterium tuberculosis by reducing ß-lactamase secretion and increasing cell envelope permeability.
Jeon AB, Obregón-Henao A, Ackart DF, Podell BK, Belardinelli JM, Jackson M, Nguyen TV, Blackledge MS, Melander RJ, Melander C, Johnson BK, Abramovitch RB, Basaraba RJ. Jeon AB, et al. Among authors: abramovitch rb. PLoS One. 2017 Jul 27;12(7):e0180925. doi: 10.1371/journal.pone.0180925. eCollection 2017. PLoS One. 2017. PMID: 28749949 Free PMC article.
54 results