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HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression.
Guha M, Srinivasan S, Guja K, Mejia E, Garcia-Diaz M, Johnson FB, Ruthel G, Kaufman BA, Rappaport EF, Glineburg MR, Fang JK, Klein-Szanto AJ, Klein Szanto A, Nakagawa H, Basha J, Kundu T, Avadhani NG. Guha M, et al. Among authors: klein szanto a, klein szanto aj. Cell Discov. 2016 Dec 6;2:16045. doi: 10.1038/celldisc.2016.45. eCollection 2016. Cell Discov. 2016. PMID: 27990297 Free PMC article.
Esophageal 3D organoids of MPV17-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition.
Guha M, Srinivasan S, Sheehan MM, Kijima T, Ruthel G, Whelan K, Tanaka K, Klein-Szanto A, Chandramouleeswaran PM, Nakagawa H, Avadhani NG. Guha M, et al. Among authors: klein szanto a. Oncotarget. 2019 Oct 22;10(58):6245-6259. doi: 10.18632/oncotarget.27264. eCollection 2019 Oct 22. Oncotarget. 2019. PMID: 31692873 Free PMC article.
Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance.
Whelan KA, Chandramouleeswaran PM, Tanaka K, Natsuizaka M, Guha M, Srinivasan S, Darling DS, Kita Y, Natsugoe S, Winkler JD, Klein-Szanto AJ, Amaravadi RK, Avadhani NG, Rustgi AK, Nakagawa H. Whelan KA, et al. Among authors: klein szanto aj. Oncogene. 2017 Aug 24;36(34):4843-4858. doi: 10.1038/onc.2017.102. Epub 2017 Apr 17. Oncogene. 2017. PMID: 28414310 Free PMC article.
Hypoxia activates the cyclooxygenase-2-prostaglandin E synthase axis.
Lee JJ, Natsuizaka M, Ohashi S, Wong GS, Takaoka M, Michaylira CZ, Budo D, Tobias JW, Kanai M, Shirakawa Y, Naomoto Y, Klein-Szanto AJ, Haase VH, Nakagawa H. Lee JJ, et al. Carcinogenesis. 2010 Mar;31(3):427-34. doi: 10.1093/carcin/bgp326. Epub 2009 Dec 30. Carcinogenesis. 2010. PMID: 20042640 Free PMC article.
Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities.
Kagawa S, Natsuizaka M, Whelan KA, Facompre N, Naganuma S, Ohashi S, Kinugasa H, Egloff AM, Basu D, Gimotty PA, Klein-Szanto AJ, Bass AJ, Wong KK, Diehl JA, Rustgi AK, Nakagawa H. Kagawa S, et al. Among authors: klein szanto aj. Oncogene. 2015 Apr 30;34(18):2347-59. doi: 10.1038/onc.2014.169. Epub 2014 Jun 16. Oncogene. 2015. PMID: 24931169 Free PMC article.
432 results