Katt WP - Search Results

1

Targeting amino acid metabolism for cancer therapy.

Lukey MJ, Katt WP, Cerione RA. Lukey MJ, et al. Among authors: katt wp. Drug Discov Today. 2017 May;22(5):796-804. doi: 10.1016/j.drudis.2016.12.003. Epub 2016 Dec 14. Drug Discov Today. 2017. PMID: 27988359 Free PMC article. Review.

2

Dibenzophenanthridines as inhibitors of glutaminase C and cancer cell proliferation.

Katt WP, Ramachandran S, Erickson JW, Cerione RA. Katt WP, et al. Mol Cancer Ther. 2012 Jun;11(6):1269-78. doi: 10.1158/1535-7163.MCT-11-0942. Epub 2012 Apr 11. Mol Cancer Ther. 2012. PMID: 22496480 Free PMC article.

3

Glutaminase regulation in cancer cells: a druggable chain of events.

Katt WP, Cerione RA. Katt WP, et al. Drug Discov Today. 2014 Apr;19(4):450-7. doi: 10.1016/j.drudis.2013.10.008. Epub 2013 Oct 16. Drug Discov Today. 2014. PMID: 24140288 Free PMC article. Review.

4

Simultaneously targeting tissue transglutaminase and kidney type glutaminase sensitizes cancer cells to acid toxicity and offers new opportunities for therapeutic intervention.

Katt WP, Antonyak MA, Cerione RA. Katt WP, et al. Mol Pharm. 2015 Jan 5;12(1):46-55. doi: 10.1021/mp500405h. Epub 2014 Dec 10. Mol Pharm. 2015. PMID: 25426679 Free PMC article.

5

Less than the sum of its parts, a leinamycin precursor has superior properties.

Katt WP, Cerione RA. Katt WP, et al. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8164-5. doi: 10.1073/pnas.1510122112. Epub 2015 Jun 23. Proc Natl Acad Sci U S A. 2015. PMID: 26106161 Free PMC article. No abstract available.

6

Design and evaluation of novel glutaminase inhibitors.

McDermott LA, Iyer P, Vernetti L, Rimer S, Sun J, Boby M, Yang T, Fioravanti M, O'Neill J, Wang L, Drakes D, Katt W, Huang Q, Cerione R. McDermott LA, et al. Bioorg Med Chem. 2016 Apr 15;24(8):1819-39. doi: 10.1016/j.bmc.2016.03.009. Epub 2016 Mar 7. Bioorg Med Chem. 2016. PMID: 26988803 Free PMC article.

7

Mechanistic Basis of Glutaminase Activation: A KEY ENZYME THAT PROMOTES GLUTAMINE METABOLISM IN CANCER CELLS.

Li Y, Erickson JW, Stalnecker CA, Katt WP, Huang Q, Cerione RA, Ramachandran S. Li Y, et al. Among authors: katt wp. J Biol Chem. 2016 Sep 30;291(40):20900-20910. doi: 10.1074/jbc.M116.720268. Epub 2016 Aug 19. J Biol Chem. 2016. PMID: 27542409 Free PMC article.

8

A tale of two glutaminases: homologous enzymes with distinct roles in tumorigenesis.

Katt WP, Lukey MJ, Cerione RA. Katt WP, et al. Future Med Chem. 2017 Jan;9(2):223-243. doi: 10.4155/fmc-2016-0190. Epub 2017 Jan 23. Future Med Chem. 2017. PMID: 28111979 Free PMC article. Review.

9

Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism.

Huang Q, Stalnecker C, Zhang C, McDermott LA, Iyer P, O'Neill J, Reimer S, Cerione RA, Katt WP. Huang Q, et al. Among authors: katt wp. J Biol Chem. 2018 Mar 9;293(10):3535-3545. doi: 10.1074/jbc.M117.810101. Epub 2018 Jan 9. J Biol Chem. 2018. PMID: 29317493 Free PMC article.

10

The diamond anniversary of tissue transglutaminase: a protein of many talents.

Katt WP, Antonyak MA, Cerione RA. Katt WP, et al. Drug Discov Today. 2018 Mar;23(3):575-591. doi: 10.1016/j.drudis.2018.01.037. Epub 2018 Jan 31. Drug Discov Today. 2018. PMID: 29362136 Free PMC article. Review.

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