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PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma.
Pytel D, Gao Y, Mackiewicz K, Katlinskaya YV, Staschke KA, Paredes MC, Yoshida A, Qie S, Zhang G, Chajewski OS, Wu L, Majsterek I, Herlyn M, Fuchs SY, Diehl JA. Pytel D, et al. Among authors: gao y. PLoS Genet. 2016 Dec 15;12(12):e1006518. doi: 10.1371/journal.pgen.1006518. eCollection 2016 Dec. PLoS Genet. 2016. PMID: 27977682 Free PMC article.
ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth.
Hart LS, Cunningham JT, Datta T, Dey S, Tameire F, Lehman SL, Qiu B, Zhang H, Cerniglia G, Bi M, Li Y, Gao Y, Liu H, Li C, Maity A, Thomas-Tikhonenko A, Perl AE, Koong A, Fuchs SY, Diehl JA, Mills IG, Ruggero D, Koumenis C. Hart LS, et al. Among authors: gao y. J Clin Invest. 2012 Dec;122(12):4621-34. doi: 10.1172/JCI62973. Epub 2012 Nov 12. J Clin Invest. 2012. PMID: 23143306 Free PMC article.
Type I interferons mediate pancreatic toxicities of PERK inhibition.
Yu Q, Zhao B, Gui J, Katlinski KV, Brice A, Gao Y, Li C, Kushner JA, Koumenis C, Diehl JA, Fuchs SY. Yu Q, et al. Among authors: gao y. Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15420-5. doi: 10.1073/pnas.1516362112. Epub 2015 Dec 1. Proc Natl Acad Sci U S A. 2015. PMID: 26627716 Free PMC article.
HIV Protease Inhibitors Alter Amyloid Precursor Protein Processing via β-Site Amyloid Precursor Protein Cleaving Enzyme-1 Translational Up-Regulation.
Gannon PJ, Akay-Espinoza C, Yee AC, Briand LA, Erickson MA, Gelman BB, Gao Y, Haughey NJ, Zink MC, Clements JE, Kim NS, Van De Walle G, Jensen BK, Vassar R, Pierce RC, Gill AJ, Kolson DL, Diehl JA, Mankowski JL, Jordan-Sciutto KL. Gannon PJ, et al. Among authors: gao y. Am J Pathol. 2017 Jan;187(1):91-109. doi: 10.1016/j.ajpath.2016.09.006. Am J Pathol. 2017. PMID: 27993242 Free PMC article.
Foxl1 promotes liver repair following cholestatic injury in mice.
Sackett SD, Gao Y, Shin S, Esterson YB, Tsingalia A, Hurtt RS, Brondell K, Kaestner KH, Greenbaum LE. Sackett SD, et al. Among authors: gao y. Lab Invest. 2009 Dec;89(12):1387-96. doi: 10.1038/labinvest.2009.103. Epub 2009 Oct 19. Lab Invest. 2009. PMID: 19841618 Free article.
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