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Corrigendum: PI3Kγ is a molecular switch that controls immune suppression.
Kaneda MM, Messer KS, Ralainirina N, Li H, Leem CJ, Gorjestani S, Woo G, Nguyen AV, Figueiredo CC, Foubert P, Schmid MC, Pink M, Winkler DG, Rausch M, Palombella VJ, Kutok J, McGovern K, Frazer KA, Wu X, Karin M, Sasik R, Cohen EE, Varner JA. Kaneda MM, et al. Among authors: foubert p. Nature. 2017 Feb 2;542(7639):124. doi: 10.1038/nature21026. Epub 2016 Dec 14. Nature. 2017. PMID: 27974794 Free PMC article. No abstract available.
PI3Kγ is a molecular switch that controls immune suppression.
Kaneda MM, Messer KS, Ralainirina N, Li H, Leem CJ, Gorjestani S, Woo G, Nguyen AV, Figueiredo CC, Foubert P, Schmid MC, Pink M, Winkler DG, Rausch M, Palombella VJ, Kutok J, McGovern K, Frazer KA, Wu X, Karin M, Sasik R, Cohen EE, Varner JA. Kaneda MM, et al. Among authors: foubert p. Nature. 2016 Nov 17;539(7629):437-442. doi: 10.1038/nature19834. Epub 2016 Sep 19. Nature. 2016. PMID: 27642729 Free PMC article.
Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression.
Kaneda MM, Cappello P, Nguyen AV, Ralainirina N, Hardamon CR, Foubert P, Schmid MC, Sun P, Mose E, Bouvet M, Lowy AM, Valasek MA, Sasik R, Novelli F, Hirsch E, Varner JA. Kaneda MM, et al. Among authors: foubert p. Cancer Discov. 2016 Aug;6(8):870-85. doi: 10.1158/2159-8290.CD-15-1346. Epub 2016 May 13. Cancer Discov. 2016. PMID: 27179037 Free PMC article.
Receptor tyrosine kinases and TLR/IL1Rs unexpectedly activate myeloid cell PI3kγ, a single convergent point promoting tumor inflammation and progression.
Schmid MC, Avraamides CJ, Dippold HC, Franco I, Foubert P, Ellies LG, Acevedo LM, Manglicmot JR, Song X, Wrasidlo W, Blair SL, Ginsberg MH, Cheresh DA, Hirsch E, Field SJ, Varner JA. Schmid MC, et al. Among authors: foubert p. Cancer Cell. 2011 Jun 14;19(6):715-27. doi: 10.1016/j.ccr.2011.04.016. Cancer Cell. 2011. PMID: 21665146 Free PMC article.
PI3Kα activates integrin α4β1 to establish a metastatic niche in lymph nodes.
Garmy-Susini B, Avraamides CJ, Desgrosellier JS, Schmid MC, Foubert P, Ellies LG, Lowy AM, Blair SL, Vandenberg SR, Datnow B, Wang HY, Cheresh DA, Varner J. Garmy-Susini B, et al. Among authors: foubert p. Proc Natl Acad Sci U S A. 2013 May 28;110(22):9042-7. doi: 10.1073/pnas.1219603110. Epub 2013 May 13. Proc Natl Acad Sci U S A. 2013. PMID: 23671068 Free PMC article.
MST1R kinase accelerates pancreatic cancer progression via effects on both epithelial cells and macrophages.
Babicky ML, Harper MM, Chakedis J, Cazes A, Mose ES, Jaquish DV, French RP, Childers B, Alakus H, Schmid MC, Foubert P, Miyamoto J, Holman PJ, Walterscheid ZJ, Tang CM, Varki N, Sicklick JK, Messer K, Varner JA, Waltz SE, Lowy AM. Babicky ML, et al. Among authors: foubert p. Oncogene. 2019 Jul;38(28):5599-5611. doi: 10.1038/s41388-019-0811-9. Epub 2019 Apr 9. Oncogene. 2019. PMID: 30967626 Free PMC article.
Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis.
Garmy-Susini B, Avraamides CJ, Schmid MC, Foubert P, Ellies LG, Barnes L, Feral C, Papayannopoulou T, Lowy A, Blair SL, Cheresh D, Ginsberg M, Varner JA. Garmy-Susini B, et al. Among authors: foubert p. Cancer Res. 2010 Apr 15;70(8):3042-51. doi: 10.1158/0008-5472.CAN-09-3761. Epub 2010 Apr 13. Cancer Res. 2010. PMID: 20388801 Free PMC article.
37 results