Snelder N - Search Results

1

Characterization and Prediction of Cardiovascular Effects of Fingolimod and Siponimod Using a Systems Pharmacology Modeling Approach.

Snelder N, Ploeger BA, Luttringer O, Rigel DF, Webb RL, Feldman D, Fu F, Beil M, Jin L, Stanski DR, Danhof M. Snelder N, et al. J Pharmacol Exp Ther. 2017 Feb;360(2):356-367. doi: 10.1124/jpet.116.236208. Epub 2016 Dec 1. J Pharmacol Exp Ther. 2017. PMID: 27934627

2

Prediction of attack frequency in migraine treatment.

Maas HJ, Snelder N, Danhof M, Della Pasqua O. Maas HJ, et al. Among authors: snelder n. Cephalalgia. 2008 Aug;28(8):847-55. doi: 10.1111/j.1468-2982.2008.01621.x. Epub 2008 Jun 6. Cephalalgia. 2008. PMID: 18540870 Clinical Trial.

3

Estimation of binding rate constants using a simultaneous mixed-effects method: application to monoamine transporter reuptake inhibitor reboxetine.

Benson N, Snelder N, Ploeger B, Napier C, Sale H, Birdsall NJ, Butt RP, van der Graaf PH. Benson N, et al. Among authors: snelder n. Br J Pharmacol. 2010 May;160(2):389-98. doi: 10.1111/j.1476-5381.2010.00719.x. Br J Pharmacol. 2010. PMID: 20423348 Free PMC article.

4

Pharmacokinetic-pharmacodynamic modeling of the antihypertensive effect of eprosartan in Black and White hypertensive patients.

van Rijn-Bikker PC, Ackaert O, Snelder N, van Hest RM, Ploeger BA, Koopmans RP, Mathôt RA. van Rijn-Bikker PC, et al. Among authors: snelder n. Clin Pharmacokinet. 2013 Sep;52(9):793-803. doi: 10.1007/s40262-013-0073-6. Clin Pharmacokinet. 2013. PMID: 23696281 Clinical Trial.

5

PKPD modelling of the interrelationship between mean arterial BP, cardiac output and total peripheral resistance in conscious rats.

Snelder N, Ploeger BA, Luttringer O, Rigel DF, Webb RL, Feldman D, Fu F, Beil M, Jin L, Stanski DR, Danhof M. Snelder N, et al. Br J Pharmacol. 2013 Aug;169(7):1510-24. doi: 10.1111/bph.12190. Br J Pharmacol. 2013. PMID: 23849040 Free PMC article.

6

Nonlinear mixed effects modeling of the diurnal blood pressure profile in a multiracial population.

van Rijn-Bikker PC, Snelder N, Ackaert O, van Hest RM, Ploeger BA, van Montfrans GA, Koopmans RP, Mathôt RA. van Rijn-Bikker PC, et al. Among authors: snelder n. Am J Hypertens. 2013 Sep;26(9):1103-13. doi: 10.1093/ajh/hpt088. Am J Hypertens. 2013. PMID: 23939415 Clinical Trial.

7

Drug effects on the CVS in conscious rats: separating cardiac output into heart rate and stroke volume using PKPD modelling.

Snelder N, Ploeger BA, Luttringer O, Rigel DF, Fu F, Beil M, Stanski DR, Danhof M. Snelder N, et al. Br J Pharmacol. 2014 Nov;171(22):5076-92. doi: 10.1111/bph.12824. Epub 2014 Sep 5. Br J Pharmacol. 2014. PMID: 24962208 Free PMC article.

8

Translational pharmacokinetic modeling of fingolimod (FTY720) as a paradigm compound subject to sphingosine kinase-mediated phosphorylation.

Snelder N, Ploeger BA, Luttringer O, Stanski DR, Danhof M. Snelder N, et al. Drug Metab Dispos. 2014 Sep;42(9):1367-78. doi: 10.1124/dmd.113.056770. Epub 2014 Jun 25. Drug Metab Dispos. 2014. PMID: 24965813

9

Population Pharmacokinetic and Exposure-Response Analysis of Finerenone: Insights Based on Phase IIb Data and Simulations to Support Dose Selection for Pivotal Trials in Type 2 Diabetes with Chronic Kidney Disease.

Snelder N, Heinig R, Drenth HJ, Joseph A, Kolkhof P, Lippert J, Garmann D, Ploeger B, Eissing T. Snelder N, et al. Clin Pharmacokinet. 2020 Mar;59(3):359-370. doi: 10.1007/s40262-019-00820-x. Clin Pharmacokinet. 2020. PMID: 31583611 Free PMC article. Clinical Trial.

10

A novel cardiovascular systems model to quantify drugs effects on the inter-relationship between contractility and other hemodynamic variables.

Fu Y, Taghvafard H, Said MM, Rossman EI, Collins TA, Billiald-Desquand S, Leishman D, van der Graaf PH, van Hasselt JGC, Snelder N. Fu Y, et al. Among authors: snelder n. CPT Pharmacometrics Syst Pharmacol. 2022 May;11(5):640-652. doi: 10.1002/psp4.12774. Epub 2022 Mar 18. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35213797 Free PMC article.

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