Wang ZH - Search Results

1

Novel Tetrahydropyrido[4,3-d]pyrimidines as Potent Inhibitors of Chaperone Heat Shock Protein 90.

Jiang F, Wang HJ, Jin YH, Zhang Q, Wang ZH, Jia JM, Liu F, Wang L, Bao QC, Li DD, You QD, Xu XL. Jiang F, et al. Among authors: wang zh, wang l, wang hj. J Med Chem. 2016 Dec 8;59(23):10498-10519. doi: 10.1021/acs.jmedchem.6b00912. Epub 2016 Nov 22. J Med Chem. 2016. PMID: 27933959

2

G9a - An Appealing Antineoplastic Target.

Chen WL, Sun HP, Li DD, Wang ZH, You QD, Guo XK. Chen WL, et al. Among authors: wang zh. Curr Cancer Drug Targets. 2017;17(6):555-568. doi: 10.2174/1568009616666160512145303. Curr Cancer Drug Targets. 2017. PMID: 27174055 Review.

3

High-affinity small molecular blockers of mixed lineage leukemia 1 (MLL1)-WDR5 interaction inhibit MLL1 complex H3K4 methyltransferase activity.

Li DD, Chen WL, Wang ZH, Xie YY, Xu XL, Jiang ZY, Zhang XJ, You QD, Guo XK. Li DD, et al. Among authors: wang zh. Eur J Med Chem. 2016 Nov 29;124:480-489. doi: 10.1016/j.ejmech.2016.08.036. Epub 2016 Aug 20. Eur J Med Chem. 2016. PMID: 27598236

4

Structure-based design of ester compounds to inhibit MLL complex catalytic activity by targeting mixed lineage leukemia 1 (MLL1)-WDR5 interaction.

Li DD, Wang ZH, Chen WL, Xie YY, You QD, Guo XK. Li DD, et al. Among authors: wang zh. Bioorg Med Chem. 2016 Nov 15;24(22):6109-6118. doi: 10.1016/j.bmc.2016.09.073. Epub 2016 Oct 1. Bioorg Med Chem. 2016. PMID: 27720555

5

Discovery, design and synthesis of 6H-anthra[1,9-cd]isoxazol-6-one scaffold as G9a inhibitor through a combination of shape-based virtual screening and structure-based molecular modification.

Chen WL, Wang ZH, Feng TT, Li DD, Wang CH, Xu XL, Zhang XJ, You QD, Guo XK. Chen WL, et al. Among authors: wang zh, wang ch. Bioorg Med Chem. 2016 Nov 15;24(22):6102-6108. doi: 10.1016/j.bmc.2016.09.071. Epub 2016 Sep 30. Bioorg Med Chem. 2016. PMID: 27720557

6

Design, synthesis, and initial evaluation of affinity-based small molecular probe for detection of WDR5.

Chen WL, Li DD, Wang ZH, Xu XL, Zhang XJ, Jiang ZY, Guo XK, You QD. Chen WL, et al. Among authors: wang zh. Bioorg Chem. 2018 Feb;76:380-385. doi: 10.1016/j.bioorg.2017.11.018. Epub 2017 Nov 28. Bioorg Chem. 2018. PMID: 29241110

7

Targeting protein-protein interaction between MLL1 and reciprocal proteins for leukemia therapy.

Wang ZH, Li DD, Chen WL, You QD, Guo XK. Wang ZH, et al. Bioorg Med Chem. 2018 Jan 15;26(2):356-365. doi: 10.1016/j.bmc.2017.11.045. Epub 2017 Dec 1. Bioorg Med Chem. 2018. PMID: 29254892 Review.

8

Progress of NIR-II fluorescence imaging technology applied to disease diagnosis and treatment.

Li N, Wang M, Zhou J, Wang Z, Cao L, Ye J, Sun G. Li N, et al. Eur J Med Chem. 2024 Mar 5;267:116173. doi: 10.1016/j.ejmech.2024.116173. Epub 2024 Jan 28. Eur J Med Chem. 2024. PMID: 38320425 Review.

9

ROS-Responsive Ferrocenyl Amphiphilic PAMAM Dendrimers for On-Demand Delivery of siRNA Therapeutics to Cancer Cells.

Chen P, Wang Z, Wang X, Gong J, Sheng J, Pan Y, Zhu D, Liu X. Chen P, et al. Pharmaceutics. 2024 Jul 13;16(7):936. doi: 10.3390/pharmaceutics16070936. Pharmaceutics. 2024. PMID: 39065632 Free PMC article.

10

Macrophages as potential targets in gene therapy for cancer treatment.

Huang Y, Wang Z, Gong J, Zhu D, Chen W, Li F, Liang XJ, Liu X. Huang Y, et al. Explor Target Antitumor Ther. 2023;4(1):89-101. doi: 10.37349/etat.2023.00124. Epub 2023 Feb 28. Explor Target Antitumor Ther. 2023. PMID: 36937317 Free PMC article. Review.

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