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510 results

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Page 1
Resistance of dynamin-related protein 1 oligomers to disassembly impairs mitophagy, resulting in myocardial inflammation and heart failure.
Cahill TJ, Leo V, Kelly M, Stockenhuber A, Kennedy NW, Bao L, Cereghetti GM, Harper AR, Czibik G, Liao C, Bellahcene M, Steeples V, Ghaffari S, Yavari A, Mayer A, Poulton J, Ferguson DJ, Scorrano L, Hettiarachchi NT, Peers C, Boyle J, Hill RB, Simmons A, Watkins H, Dear TN, Ashrafian H. Cahill TJ, et al. Among authors: ferguson dj. J Biol Chem. 2016 Dec 2;291(49):25762. doi: 10.1074/jbc.A115.665695. J Biol Chem. 2016. PMID: 27913663 Free PMC article. No abstract available.
Resistance of Dynamin-related Protein 1 Oligomers to Disassembly Impairs Mitophagy, Resulting in Myocardial Inflammation and Heart Failure.
Cahill TJ, Leo V, Kelly M, Stockenhuber A, Kennedy NW, Bao L, Cereghetti GM, Harper AR, Czibik G, Liao C, Bellahcene M, Steeples V, Ghaffari S, Yavari A, Mayer A, Poulton J, Ferguson DJ, Scorrano L, Hettiarachchi NT, Peers C, Boyle J, Hill RB, Simmons A, Watkins H, Dear TN, Ashrafian H. Cahill TJ, et al. Among authors: ferguson dj. J Biol Chem. 2015 Oct 23;290(43):25907-19. doi: 10.1074/jbc.M115.665695. Epub 2015 Sep 14. J Biol Chem. 2015. PMID: 26370078 Free PMC article.
Mammalian γ2 AMPK regulates intrinsic heart rate.
Yavari A, Bellahcene M, Bucchi A, Sirenko S, Pinter K, Herring N, Jung JJ, Tarasov KV, Sharpe EJ, Wolfien M, Czibik G, Steeples V, Ghaffari S, Nguyen C, Stockenhuber A, Clair JRS, Rimmbach C, Okamoto Y, Yang D, Wang M, Ziman BD, Moen JM, Riordon DR, Ramirez C, Paina M, Lee J, Zhang J, Ahmet I, Matt MG, Tarasova YS, Baban D, Sahgal N, Lockstone H, Puliyadi R, de Bono J, Siggs OM, Gomes J, Muskett H, Maguire ML, Beglov Y, Kelly M, Dos Santos PPN, Bright NJ, Woods A, Gehmlich K, Isackson H, Douglas G, Ferguson DJP, Schneider JE, Tinker A, Wolkenhauer O, Channon KM, Cornall RJ, Sternick EB, Paterson DJ, Redwood CS, Carling D, Proenza C, David R, Baruscotti M, DiFrancesco D, Lakatta EG, Watkins H, Ashrafian H. Yavari A, et al. Among authors: ferguson djp. Nat Commun. 2017 Nov 2;8(1):1258. doi: 10.1038/s41467-017-01342-5. Nat Commun. 2017. PMID: 29097735 Free PMC article.
iASPP, a previously unidentified regulator of desmosomes, prevents arrhythmogenic right ventricular cardiomyopathy (ARVC)-induced sudden death.
Notari M, Hu Y, Sutendra G, Dedeić Z, Lu M, Dupays L, Yavari A, Carr CA, Zhong S, Opel A, Tinker A, Clarke K, Watkins H, Ferguson DJ, Kelsell DP, de Noronha S, Sheppard MN, Hollinshead M, Mohun TJ, Lu X. Notari M, et al. Among authors: ferguson dj. Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):E973-81. doi: 10.1073/pnas.1408111112. Epub 2015 Feb 17. Proc Natl Acad Sci U S A. 2015. PMID: 25691752 Free PMC article.
A novel SUN1-ALLAN complex coordinates segregation of the bipartite MTOC across the nuclear envelope during rapid closed mitosis in Plasmodium.
Zeeshan M, Blatov I, Yanase R, Ferguson DJP, Pashley SL, Chahine Z, Botté YY, Mishra A, Marché B, Bhanvadia S, Hair M, Batra S, Markus R, Brady D, Bottrill A, Vaughan S, Botté CY, Roch KL, Holder AA, Tromer EC, Tewari R. Zeeshan M, et al. Among authors: ferguson djp. bioRxiv [Preprint]. 2024 Dec 5:2024.12.04.625416. doi: 10.1101/2024.12.04.625416. bioRxiv. 2024. PMID: 39677758 Free PMC article. Preprint.
Plasmodium NEK1 coordinates MTOC organisation and kinetochore attachment during rapid mitosis in male gamete formation.
Zeeshan M, Rashpa R, Ferguson DJ, Mckeown G, Nugmanova R, Subudhi AK, Beyeler R, Pashley SL, Markus R, Brady D, Roques M, Bottrill AR, Fry AM, Pain A, Vaughan S, Holder AA, Tromer EC, Brochet M, Tewari R. Zeeshan M, et al. Among authors: ferguson dj. PLoS Biol. 2024 Sep 10;22(9):e3002802. doi: 10.1371/journal.pbio.3002802. eCollection 2024 Sep. PLoS Biol. 2024. PMID: 39255311 Free PMC article.
DNA-binding protein PfAP2-P regulates parasite pathogenesis during malaria parasite blood stages.
Subudhi AK, Green JL, Satyam R, Salunke RP, Lenz T, Shuaib M, Isaioglou I, Abel S, Gupta M, Esau L, Mourier T, Nugmanova R, Mfarrej S, Shivapurkar R, Stead Z, Rached FB, Ostwal Y, Sougrat R, Dada A, Kadamany AF, Fischle W, Merzaban J, Knuepfer E, Ferguson DJP, Gupta I, Le Roch KG, Holder AA, Pain A. Subudhi AK, et al. Among authors: ferguson djp. Nat Microbiol. 2023 Nov;8(11):2154-2169. doi: 10.1038/s41564-023-01497-6. Epub 2023 Oct 26. Nat Microbiol. 2023. PMID: 37884813 Free PMC article.
PfAP2-MRP DNA-binding protein is a master regulator of parasite pathogenesis during malaria parasite blood stages.
Subudhi AK, Green JL, Satyam R, Lenz T, Salunke RP, Shuaib M, Isaioglou I, Abel S, Gupta M, Esau L, Mourier T, Nugmanova R, Mfarrej S, Sivapurkar R, Stead Z, Rached FB, Otswal Y, Sougrat R, Dada A, Kadamany AF, Fischle W, Merzaban J, Knuepfer E, Ferguson DJP, Gupta I, Le Roch KG, Holder AA, Pain A. Subudhi AK, et al. Among authors: ferguson djp. bioRxiv [Preprint]. 2023 May 24:2023.05.23.541898. doi: 10.1101/2023.05.23.541898. bioRxiv. 2023. Update in: Nat Microbiol. 2023 Nov;8(11):2154-2169. doi: 10.1038/s41564-023-01497-6 PMID: 37293082 Free PMC article. Updated. Preprint.
510 results