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Premorbid obesity, but not nutrition, prevents critical illness-induced muscle wasting and weakness.
Goossens C, Marques MB, Derde S, Vander Perre S, Dufour T, Thiessen SE, Güiza F, Janssens T, Hermans G, Vanhorebeek I, De Bock K, Van den Berghe G, Langouche L. Goossens C, et al. Among authors: de bock k. J Cachexia Sarcopenia Muscle. 2017 Feb;8(1):89-101. doi: 10.1002/jcsm.12131. Epub 2016 Jul 20. J Cachexia Sarcopenia Muscle. 2017. PMID: 27897405 Free PMC article.
Combinatorial Treatment with PARP and MAPK Inhibitors Overcomes Phenotype Switch-Driven Drug Resistance in Advanced Melanoma.
Ferretti LP, Böhi F, Leslie Pedrioli DM, Cheng PF, Ferrari E, Baumgaertner P, Alvarado-Diaz A, Sella F, Cereghetti A, Turko P, Wright RH, De Bock K, Speiser DE, Ferrari R, Levesque MP, Hottiger MO. Ferretti LP, et al. Among authors: de bock k. Cancer Res. 2023 Dec 1;83(23):3974-3988. doi: 10.1158/0008-5472.CAN-23-0485. Cancer Res. 2023. PMID: 37729428
Mitochondria in peroxisome-deficient hepatocytes exhibit impaired respiration, depleted DNA, and PGC-1α independent proliferation.
Peeters A, Shinde AB, Dirkx R, Smet J, De Bock K, Espeel M, Vanhorebeek I, Vanlander A, Van Coster R, Carmeliet P, Fransen M, Van Veldhoven PP, Baes M. Peeters A, et al. Among authors: de bock k. Biochim Biophys Acta. 2015 Feb;1853(2):285-98. doi: 10.1016/j.bbamcr.2014.11.017. Epub 2014 Nov 20. Biochim Biophys Acta. 2015. PMID: 25450972 Free article.
Mice deficient in the respiratory chain gene Cox6a2 are protected against high-fat diet-induced obesity and insulin resistance.
Quintens R, Singh S, Lemaire K, De Bock K, Granvik M, Schraenen A, Vroegrijk IO, Costa V, Van Noten P, Lambrechts D, Lehnert S, Van Lommel L, Thorrez L, De Faudeur G, Romijn JA, Shelton JM, Scorrano L, Lijnen HR, Voshol PJ, Carmeliet P, Mammen PP, Schuit F. Quintens R, et al. Among authors: de bock k, de faudeur g. PLoS One. 2013;8(2):e56719. doi: 10.1371/journal.pone.0056719. Epub 2013 Feb 27. PLoS One. 2013. PMID: 23460811 Free PMC article.
95 results