Waaler J - Search Results

1

Versatile, sensitive liquid chromatography mass spectrometry - Implementation of 10 μm OT columns suitable for small molecules, peptides and proteins.

Vehus T, Roberg-Larsen H, Waaler J, Aslaksen S, Krauss S, Wilson SR, Lundanes E. Vehus T, et al. Among authors: waaler j. Sci Rep. 2016 Nov 29;6:37507. doi: 10.1038/srep37507. Sci Rep. 2016. PMID: 27897190 Free PMC article.

2

Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth.

Waaler J, Machon O, von Kries JP, Wilson SR, Lundenes E, Wedlich D, Gradl D, Paulsen JE, Machonova O, Dembinski JL, Dinh H, Krauss S. Waaler J, et al. Cancer Res. 2011 Jan 1;71(1):197-205. doi: 10.1158/0008-5472.CAN-10-1282. Cancer Res. 2011. PMID: 21199802

3

A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice.

Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, Paulsen JE, Pedersen NM, Eide TJ, Machonova O, Gradl D, Voronkov A, von Kries JP, Krauss S. Waaler J, et al. Cancer Res. 2012 Jun 1;72(11):2822-32. doi: 10.1158/0008-5472.CAN-11-3336. Epub 2012 Mar 22. Cancer Res. 2012. PMID: 22440753

4

Structural basis and SAR for G007-LK, a lead stage 1,2,4-triazole based specific tankyrase 1/2 inhibitor.

Voronkov A, Holsworth DD, Waaler J, Wilson SR, Ekblad B, Perdreau-Dahl H, Dinh H, Drewes G, Hopf C, Morth JP, Krauss S. Voronkov A, et al. Among authors: waaler j. J Med Chem. 2013 Apr 11;56(7):3012-23. doi: 10.1021/jm4000566. Epub 2013 Mar 29. J Med Chem. 2013. PMID: 23473363

5

The tankyrase-specific inhibitor JW74 affects cell cycle progression and induces apoptosis and differentiation in osteosarcoma cell lines.

Stratford EW, Daffinrud J, Munthe E, Castro R, Waaler J, Krauss S, Myklebost O. Stratford EW, et al. Among authors: waaler j. Cancer Med. 2014 Feb;3(1):36-46. doi: 10.1002/cam4.170. Epub 2013 Dec 17. Cancer Med. 2014. PMID: 24403055 Free PMC article.

6

Structure, Dynamics, and Functionality of Tankyrase Inhibitor-Induced Degradasomes.

Thorvaldsen TE, Pedersen NM, Wenzel EM, Schultz SW, Brech A, Liestøl K, Waaler J, Krauss S, Stenmark H. Thorvaldsen TE, et al. Among authors: waaler j. Mol Cancer Res. 2015 Nov;13(11):1487-501. doi: 10.1158/1541-7786.MCR-15-0125. Epub 2015 Jun 29. Mol Cancer Res. 2015. PMID: 26124443 Free article.

7

Development and structural analysis of adenosine site binding tankyrase inhibitors.

Haikarainen T, Waaler J, Ignatev A, Nkizinkiko Y, Venkannagari H, Obaji E, Krauss S, Lehtiö L. Haikarainen T, et al. Among authors: waaler j. Bioorg Med Chem Lett. 2016 Jan 15;26(2):328-333. doi: 10.1016/j.bmcl.2015.12.018. Epub 2015 Dec 8. Bioorg Med Chem Lett. 2016. PMID: 26706174 Free article.

8

TANKYRASE Inhibition Enhances the Antiproliferative Effect of PI3K and EGFR Inhibition, Mutually Affecting β-CATENIN and AKT Signaling in Colorectal Cancer.

Solberg NT, Waaler J, Lund K, Mygland L, Olsen PA, Krauss S. Solberg NT, et al. Among authors: waaler j. Mol Cancer Res. 2018 Mar;16(3):543-553. doi: 10.1158/1541-7786.MCR-17-0362. Epub 2017 Dec 8. Mol Cancer Res. 2018. PMID: 29222171 Free article.

9

The tankyrase inhibitor G007-LK inhibits small intestine LGR5⁺ stem cell proliferation without altering tissue morphology.

Norum JH, Skarpen E, Brech A, Kuiper R, Waaler J, Krauss S, Sørlie T. Norum JH, et al. Among authors: waaler j. Biol Res. 2018 Jan 9;51(1):3. doi: 10.1186/s40659-017-0151-6. Biol Res. 2018. PMID: 29316982 Free PMC article.

10

A Small-Molecule Tankyrase Inhibitor Reduces Glioma Stem Cell Proliferation and Sphere Formation.

Kierulf-Vieira KS, Sandberg CJ, Waaler J, Lund K, Skaga E, Saberniak BM, Panagopoulos I, Brandal P, Krauss S, Langmoen IA, Vik-Mo EO. Kierulf-Vieira KS, et al. Among authors: waaler j. Cancers (Basel). 2020 Jun 19;12(6):1630. doi: 10.3390/cancers12061630. Cancers (Basel). 2020. PMID: 32575464 Free PMC article.

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