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Synthesis and in vivo validation of [O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)piperazin- 1-yl]butyl}-4-methyl-2H-[1,2,4]triazine-3,5-dione: a novel 5-HT1A receptor agonist positron emission tomography ligand.
Kumar JS, Majo VJ, Hsiung SC, Millak MS, Liu KP, Tamir H, Prabhakaran J, Simpson NR, Van Heertum RL, Mann JJ, Parsey RV. Kumar JS, et al. Among authors: prabhakaran j. J Med Chem. 2006 Jan 12;49(1):125-34. doi: 10.1021/jm050725j. J Med Chem. 2006. PMID: 16392798
Synthesis, in vitro and in vivo evaluation of [O-methyl-11C] 2-{4-[4-(3-methoxyphenyl)piperazin-1-yl]-butyl}-4-methyl-2H-[1,2,4]-triazine-3,5-dione: a novel agonist 5-HT1A receptor PET ligand.
Prabhakaran J, Parsey RV, Majo VJ, Hsiung SC, Milak MS, Tamir H, Simpson NR, Van Heertum RL, Mann JJ, Dileep Kumar JS. Prabhakaran J, et al. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2101-4. doi: 10.1016/j.bmcl.2006.01.052. Epub 2006 Feb 3. Bioorg Med Chem Lett. 2006. PMID: 16458504
56 results