van Echten-Deckert G - Search Results

1

Sphingosine 1-phosphate lyase ablation disrupts presynaptic architecture and function via an ubiquitin- proteasome mediated mechanism.

Mitroi DN, Deutschmann AU, Raucamp M, Karunakaran I, Glebov K, Hans M, Walter J, Saba J, Gräler M, Ehninger D, Sopova E, Shupliakov O, Swandulla D, van Echten-Deckert G. Mitroi DN, et al. Sci Rep. 2016 Nov 24;6:37064. doi: 10.1038/srep37064. Sci Rep. 2016. PMID: 27883090 Free PMC article.

2

Sphingosine-1-phosphate links glycosphingolipid metabolism to neurodegeneration via a calpain-mediated mechanism.

Hagen N, Hans M, Hartmann D, Swandulla D, van Echten-Deckert G. Hagen N, et al. Cell Death Differ. 2011 Aug;18(8):1356-65. doi: 10.1038/cdd.2011.7. Epub 2011 Feb 18. Cell Death Differ. 2011. PMID: 21331079 Free PMC article.

3

Sphingosine 1-phosphate (S1P) lyase deficiency increases sphingolipid formation via recycling at the expense of de novo biosynthesis in neurons.

Hagen-Euteneuer N, Lütjohann D, Park H, Merrill AH Jr, van Echten-Deckert G. Hagen-Euteneuer N, et al. J Biol Chem. 2012 Mar 16;287(12):9128-36. doi: 10.1074/jbc.M111.302380. Epub 2012 Jan 30. J Biol Chem. 2012. PMID: 22291021 Free PMC article.

4

Sphingolipids: critical players in Alzheimer's disease.

van Echten-Deckert G, Walter J. van Echten-Deckert G, et al. Prog Lipid Res. 2012 Oct;51(4):378-93. doi: 10.1016/j.plipres.2012.07.001. Epub 2012 Jul 23. Prog Lipid Res. 2012. PMID: 22835784 Review.

5

Cross-talk of membrane lipids and Alzheimer-related proteins.

Walter J, van Echten-Deckert G. Walter J, et al. Mol Neurodegener. 2013 Oct 22;8:34. doi: 10.1186/1750-1326-8-34. Mol Neurodegener. 2013. PMID: 24148205 Free PMC article. Review.

6

Deficiency of sphingosine-1-phosphate lyase impairs lysosomal metabolism of the amyloid precursor protein.

Karaca I, Tamboli IY, Glebov K, Richter J, Fell LH, Grimm MO, Haupenthal VJ, Hartmann T, Gräler MH, van Echten-Deckert G, Walter J. Karaca I, et al. J Biol Chem. 2014 Jun 13;289(24):16761-72. doi: 10.1074/jbc.M113.535500. Epub 2014 May 7. J Biol Chem. 2014. PMID: 24808180 Free PMC article.

7

Sphingosine-1-phosphate: boon and bane for the brain.

van Echten-Deckert G, Hagen-Euteneuer N, Karaca I, Walter J. van Echten-Deckert G, et al. Cell Physiol Biochem. 2014;34(1):148-57. doi: 10.1159/000362991. Epub 2014 Jun 16. Cell Physiol Biochem. 2014. PMID: 24977488 Free article. Review.

8

Characterization of cholesterol homeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts reveals a Niemann-Pick disease type C-like phenotype with enhanced lysosomal Ca²⁺ storage.

Vienken H, Mabrouki N, Grabau K, Claas RF, Rudowski A, Schömel N, Pfeilschifter J, Lütjohann D, van Echten-Deckert G, Meyer Zu Heringdorf D. Vienken H, et al. Sci Rep. 2017 Mar 6;7:43575. doi: 10.1038/srep43575. Sci Rep. 2017. PMID: 28262793 Free PMC article.

9

Sphingosine 1-phosphate - A double edged sword in the brain.

Karunakaran I, van Echten-Deckert G. Karunakaran I, et al. Biochim Biophys Acta Biomembr. 2017 Sep;1859(9 Pt B):1573-1582. doi: 10.1016/j.bbamem.2017.03.008. Epub 2017 Mar 14. Biochim Biophys Acta Biomembr. 2017. PMID: 28315304 Free article. Review.

10

SGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production.

Mitroi DN, Karunakaran I, Gräler M, Saba JD, Ehninger D, Ledesma MD, van Echten-Deckert G. Mitroi DN, et al. Autophagy. 2017 May 4;13(5):885-899. doi: 10.1080/15548627.2017.1291471. Autophagy. 2017. PMID: 28521611 Free PMC article.

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