Igea A - Search Results

1

Quantification of Pathway Cross-talk Reveals Novel Synergistic Drug Combinations for Breast Cancer.

Jaeger S, Igea A, Arroyo R, Alcalde V, Canovas B, Orozco M, Nebreda AR, Aloy P. Jaeger S, et al. Among authors: igea a. Cancer Res. 2017 Jan 15;77(2):459-469. doi: 10.1158/0008-5472.CAN-16-0097. Epub 2016 Nov 22. Cancer Res. 2017. PMID: 27879272

2

Expression and functional validation of new p38α transcriptional targets in tumorigenesis.

Swat A, Dolado I, Igea A, Gomez-Lopez G, Pisano DG, Cuadrado A, Nebreda AR. Swat A, et al. Among authors: igea a. Biochem J. 2011 Mar 15;434(3):549-58. doi: 10.1042/BJ20101410. Biochem J. 2011. PMID: 21226672

3

Lipid binding by the Unique and SH3 domains of c-Src suggests a new regulatory mechanism.

Pérez Y, Maffei M, Igea A, Amata I, Gairí M, Nebreda AR, Bernadó P, Pons M. Pérez Y, et al. Among authors: igea a. Sci Rep. 2013;3:1295. doi: 10.1038/srep01295. Sci Rep. 2013. PMID: 23416516 Free PMC article.

4

Multi-phosphorylation of the intrinsically disordered unique domain of c-Src studied by in-cell and real-time NMR spectroscopy.

Amata I, Maffei M, Igea A, Gay M, Vilaseca M, Nebreda AR, Pons M. Amata I, et al. Among authors: igea a. Chembiochem. 2013 Sep 23;14(14):1820-7. doi: 10.1002/cbic.201300139. Epub 2013 Jun 6. Chembiochem. 2013. PMID: 23744817

5

Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK.

Pereira L, Igea A, Canovas B, Dolado I, Nebreda AR. Pereira L, et al. Among authors: igea a. EMBO Mol Med. 2013 Nov;5(11):1759-74. doi: 10.1002/emmm.201302732. Epub 2013 Sep 24. EMBO Mol Med. 2013. PMID: 24115572 Free PMC article.

6

Dual function of p38α MAPK in colon cancer: suppression of colitis-associated tumor initiation but requirement for cancer cell survival.

Gupta J, del Barco Barrantes I, Igea A, Sakellariou S, Pateras IS, Gorgoulis VG, Nebreda AR. Gupta J, et al. Among authors: igea a. Cancer Cell. 2014 Apr 14;25(4):484-500. doi: 10.1016/j.ccr.2014.02.019. Epub 2014 Mar 27. Cancer Cell. 2014. PMID: 24684847 Free article.

7

Pharmacological inhibition of p38 MAPK reduces tumor growth in patient-derived xenografts from colon tumors.

Gupta J, Igea A, Papaioannou M, Lopez-Casas PP, Llonch E, Hidalgo M, Gorgoulis VG, Nebreda AR. Gupta J, et al. Among authors: igea a. Oncotarget. 2015 Apr 20;6(11):8539-51. doi: 10.18632/oncotarget.3816. Oncotarget. 2015. PMID: 25890501 Free PMC article.

8

Targeting of non-oncogene addiction.

Igea A, Gupta J, Nebreda AR. Igea A, et al. Aging (Albany NY). 2015 Aug;7(8):525-6. doi: 10.18632/aging.100796. Aging (Albany NY). 2015. PMID: 26298432 Free PMC article. No abstract available.

9

The Stress Kinase p38α as a Target for Cancer Therapy.

Igea A, Nebreda AR. Igea A, et al. Cancer Res. 2015 Oct 1;75(19):3997-4002. doi: 10.1158/0008-5472.CAN-15-0173. Epub 2015 Sep 16. Cancer Res. 2015. PMID: 26377941 Review.

10

Essential role of the Cdk2 activator RingoA in meiotic telomere tethering to the nuclear envelope.

Mikolcevic P, Isoda M, Shibuya H, del Barco Barrantes I, Igea A, Suja JA, Shackleton S, Watanabe Y, Nebreda AR. Mikolcevic P, et al. Among authors: igea a. Nat Commun. 2016 Mar 30;7:11084. doi: 10.1038/ncomms11084. Nat Commun. 2016. PMID: 27025256 Free PMC article.

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